Epistemis

Kidney development

Embryology · Urogenital

At E10.5, the metanephric mesenchyme (red) comprises a unique subpopulation of the nephrogenic cord (yellow). Expression of the Glial-derived neurotrophic factor (Gdnf) is restricted to the metanephric mesenchyme by the actions of transcriptional activators, secreted factors, and inhibitors. GDNF binds the Ret receptor and promotes the formation of the ureteric bud, an outgrowth from the nephric du
At E10.5, the metanephric mesenchyme (red) comprises a unique subpopulation of the nephrogenic cord (yellow). Expression of the Glial-derived neurotrophic factor (Gdnf) is…

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Category
Urogenital
Difficulty
advanced
Type
Diagram

Origin: Davidson, A.J., Mouse kidney development (January 15, 2009), StemBook, ed. The Stem Cell Research Community, StemBook, d · CC BY 3.0 · Wikimedia Commons · License CC BY 3.0

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