Epistemis

Gastric adenocarcinoma (signet ring cells)

Histology · Gastrointestinal

This tumor included a tiny proportion of signet-ring cells. These can be very "signety" and fool you into seeking a gastric primary that does not exist. I have even seen such a case present primarily as a signet ring cell carcinoma of the endometrium on a D&C specimen. It took quite a while and not a few phone calls to get to the bottom of that! Pathological and histological images courtesy of
This tumor included a tiny proportion of signet-ring cells. These can be very "signety" and fool you into seeking a gastric primary that does not exist. I have even seen such a…

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Epistemis explains the visible findings, their rationale, and important mimics through guided interpretation and clinical pearls. Free and available offline.

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Epistemis is educational review material. It is not a medical device, does not diagnose or prescribe treatment, and does not replace formal medical training, current clinical guidelines, or professional clinical judgment.

Category
Gastrointestinal
Difficulty
advanced
Type
Pathology
Taint
H&E

Origin: Ed Uthman from Houston, TX, USA · CC BY 2.0 · Wikimedia Commons · License CC BY 2.0

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