Epistemis

Autoimmunity

Immunology · Hypersensitivity

During primary infection EBV infects autoreactive naïve B cells in the tonsil, driving them to enter germinal centers where they proliferate and differentiate into latently infected autoreactive memory B cells (path 1) which then exit from the tonsil and circulate in the blood (path 2). The number of EBV-infected B cells is normally controlled by EBV-specific cytotoxic CD8+ T cells, which kill pro
During primary infection EBV infects autoreactive naïve B cells in the tonsil, driving them to enter germinal centers where they proliferate and differentiate into latently…

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PreviousType I hypersensitivity (allergy)
Category
Hypersensitivity
Difficulty
advanced
Type
Diagram

Origin: Michael P. Pender · CC BY 4.0 · Wikimedia Commons · License CC BY 4.0

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