Epistemis

Equianalgesic Opioid Converter with Cross Tolerance Adjustment

Safe transition between compounds with adjustment of the risk of respiratory depression.

Required inputs

The inputs this calculator asks for inside the app.
VariableExample value
Opioid of Origin (Current)
Daily Source Dose (mg/day)60
Target Opioid (New)
Reduction due to Incomplete Cross Tolerance (%)33

Run the calculation in the app

This page explains the score but does not run it. In Epistemis, the calculator validates units, flags values outside physiological ranges, and provides the interpretation that a number alone cannot convey.

Epistemis is educational review material. It is not a medical device, does not diagnose or prescribe treatment, and does not replace formal medical training, current clinical guidelines, or professional clinical judgment.

Specialty
Pharmacology and Dosage
Area
Clinical Bases
Variables
4
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