Epistemis

HScore calculator for LHH

Enter biological parameters to calculate the cumulative probability of reactive HLH.

Required inputs

The inputs this calculator asks for inside the app.
VariableExample value
Previous Known Immunosuppression
Maximum Body Temperature
Detectable organomegaly
Number of Cytopenias (Hb<9.2, Plt<110k, Leukos<4k)
Serum Ferritin (ng/mL)
Triglycerides (mg/dL)
Fibrinogen (mg/dL)
Glutamic-Oxalacetic Transaminase (GOT / AST in U/L)
Presence of Hemophagocytosis in the Bone Marrow

Run the calculation in the app

This page explains the score but does not run it. In Epistemis, the calculator validates units, flags values outside physiological ranges, and provides the interpretation that a number alone cannot convey.

Epistemis is educational review material. It is not a medical device, does not diagnose or prescribe treatment, and does not replace formal medical training, current clinical guidelines, or professional clinical judgment.

Specialty
Hematology
Area
Internal Medicine
Variables
9
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