Epistemis

Allergology — Allergic Cutaneous Pathology

Allergology and Immunology · Clinical Specialties

How it begins

Fisiología inmunocutánea, dermatitis atópica, urticaria, angioedema, dermatitis por contacto, reacciones adversas farmacológicas graves (SCARs), síndromes autoinflamatorios cutáneos, biomarcadores y terapéutica de última generación.

What it covers

  1. Immunophysiology of the Skin Barrier
  2. · Structural and Molecular Components of the Barrier
  3. · Epithelial Maturation and Keratinic Dynamics
  4. · Epidermal Immunology and Alarm Cascades (Alarminas)
  5. Atopic Dermatitis: Immunopathology and Phenotypes
  6. · The Dual Hypothesis: "Inside-Out" vs "Outside-In"
  7. · Immunological Phases of Atopic Dermatitis
  8. · Cytokine Signaling Pathways in AD
  9. · Clinical Endotypes and Phenotypes
  10. · Grading and Severity Systems of Atopic Dermatitis
  11. Urticaria and Angioedema: Mast Cell Physiopathology
  12. · Mast Cell Activation Mechanisms
  13. · Physiology of the Mast Cell Mediator
  14. Diagnosis and Management Algorithms
  15. · Activity Recording Systems: UAS7
  16. · Therapeutic Algorithm for Chronic Urticaria (Global Consensus)
  17. Hereditary Angioedema: C1-Inhibitor Deficiency
  18. · Pathophysiology of the Contact System (Callicrein-Kinin)
  19. · Phenotypic and Genotypic Classification of HAE
  20. · Specific Therapeutic Management
  21. Allergic Contact Dermatitis (ACD)
  22. · Pathophysiology of Haptenization and Antigenic Presentation
  23. Common Allergens and Patch Tests
  24. · Analysis of Prevalent Contact Allergens
  25. · Clinical Application and Reading Protocol (TRUE Test / GEIDAC)
  26. · International Morphological Grading (ICDRG Criteria)
  27. Contact Dermatitis: Allergic vs Irritative
  28. Serious Adverse Skin Drug Reactions (SCARs)
  29. · Diagnostic and Severity Profiles in SCARs
  30. · Detailed Molecular Physiopathology
  31. · Precision Pharmacogenetic Associations (HLA Haplotypes)
  32. Professional and Occupational Dermatoses
  33. · Allergy to Natural Rubber Latex (NRL)
  34. Immune Dysregulation and Autoinflammatory Syndromes
  35. · Cryopyrin Associated Periodic Syndromes (CAPS)
  36. · Neutrophilic Urticarial Dermatoses (NUD)
  37. In Vivo and In Vitro Diagnostic Tests
  38. · Epicutaneous Puncture Tests (Prick Test) and Intradermorreaction
  39. · Molecular Component Diagnosis (CRD)
  40. · Basophil Activation Test (TAB / BAT)
  41. New Therapeutic Targets and Precision Medicine
  42. · Arsenal of Next Generation Monoclonal (Biological) Antibodies
  43. · Janus Kinase Inhibitors (JAK Inhibitors / Oral Small Molecules)
  44. Skin-Systemic Emergencies: Anaphylaxis
  45. · Universal Clinical Diagnostic Criteria (WAO / EAACI)
  46. · Immediate Emergency Action Protocol
  47. · Second Line Treatments (Should never delay Adrenaline)

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Allergology and Immunology
Category
Clinical Specialties
Type
Study Guide
Sections
47
Reviewed
2026-08-02
Download Epistemis