Antifungals: Mechanisms of Action, Pharmacology, and Resistance — Medical Microbiology

Microbiology · Basic Sciences

How it begins

Polienos (anfotericina B desoxicolato vs liposomal), azoles y citocromo P450, equinocandinas bactericidas, flucitosina, terbinafina y resistencia FKS.

What it covers

1. 1. Polienos: Anfotericina B Desoxicolato vs Liposomal y Nistatina
2. 2. Azoles: Fluconazol, Itraconazol, Voriconazol, Posaconazol e Isavuconazol
3. · Systematic Comparison of Triazoles in Clinical Use
4. 3. Equinocandinas: Caspofungina, Micafungina y Anidulafungina
5. 4. Flucitosina y Terbinafina
6. 5. Molecular Mechanisms of Fungal Resistance to Antifungals
7. 6. Detailed Pharmacotherapeutic Guide, Dosing, and PK/PD Monitoring
8. 7. Diagnostic Yield, Sensitivity, and Preanalytical Quality Control
9. 8. Biosafety, Isolation, and Transmission Prevention Protocols
10. 9. Resistance Genomics and Ambler Molecular Classification of Beta-Lactamases
11. 10. Clinical Infectious Immunology: Cytokines, Complement, and Th1/Th17 Axis
12. 11. Extended Bank of Integrated Clinical Reasoning Cases
13. 12. High-Yield Clinical Pearls and Frequent Exam Questions
14. 13. Detailed Pharmacotherapeutic Guide, Dosing, and PK/PD Monitoring
15. 14. Diagnostic Yield, Sensitivity, and Preanalytical Quality Control
16. 15. Biosafety, Isolation, and Transmission Prevention Protocols
17. 16. Resistance Genomics and Ambler Molecular Classification of Beta-Lactamases
18. 17. Clinical Infectious Immunology: Cytokines, Complement, and Th1/Th17 Axis
19. 18. Antiviral and Antifungal Resistance: Mechanisms and Emergence of Candida auris