Clinical Biochemistry — Insulin & C Peptide

Biochemistry · Basic Sciences

How it begins

Análisis integral de la biosíntesis, estructura molecular, mecanismo de acción, interpretación de laboratorio y aplicaciones diagnósticas en la práctica clínica.

What it covers

1. Insulin Synthesis
2. · Comparison of Precursors
3. Structure of Insulin
4. Regulation of Secretion
5. · K ATP Mechanism of Glucose-Secretion Coupling
6. · Biphasic Secretion and Clinical Patterns
7. · Secretion Modulators
8. Insulin Receptor Signaling
9. · Post-receiver Signaling Pathways
10. · Tissue Effects of Insulin
11. C Peptide Biology
12. · Biological Effects of Peptide C
13. · Why We Measure C Peptide Instead of Insulin
14. Determination in the Laboratory
15. · Preanalytical Conditions
16. · Reference Values
17. · Glucagon Stimulation Test (Pancreatic β Reserve)
18. · COTG with Insulin/C Peptide Profile (75g Glucose)
19. Insulin Resistance
20. · Insulin Resistance Indices
21. · Molecular Mechanisms of Insulin Resistance
22. · Metabolic Syndrome — ATP-III and IDF Criteria
23. Classification and Diagnosis
24. · ADA 2024 Diagnostic Criteria
25. Insulin Axis Pathologies
26. · Insulinoma
27. · Differential Diagnosis of Hyperinsulinemic Hypoglycemia
28. · Other Conditions with Insulin/C Peptide Alterations
29. Clinical Interpretation Algorithm
30. · Summary — Diagnostic Patterns of Insulin and C Peptide
31. · Frequent Errors in Interpretation
32. · Medicines That Affect Insulinemia and C Peptide