Surgery: Pathophysiological Bases and Perioperative Management
Surgery · Clinical Specialties
How it begins
Estudio exhaustivo de la respuesta sistémica a la agresión quirúrgica, la evaluación y optimización del riesgo perioperatorio, y el manejo racional del paciente quirúrgico desde la valoración preoperatoria hasta la recuperación postoperatoria.
What it covers
- Pathophysiological Bases and Perioperative Management
- The Surgical Patient as a Model of Physiological Stress
- Metabolic Phases of the Surgical Response: Cuthbertson and Moore
- · Cuthbertson's two-phase model: "Ebb and Flow"
- Neuroendocrine Response to Surgical Aggression
- · Sympathetic nervous system and catecholamines
- · Hypothalamic-pituitary-adrenal axis
- Systemic Inflammatory Response to Surgical Trauma
- · Cytokine cascade
- · Acute phase proteins
- · SIRS and its relationship with surgical trauma
- Catabolism and Substrate Metabolism in the Surgical Patient
- · Stress hyperglycemia
- · Protein catabolism and nitrogen balance
- · Lipid metabolism
- Perioperative Hydroelectrolyte Balance Alterations
- · The "third space" phenomenon
- · Sodium and water retention
- · Potassium alterations
- Perioperative Thermoregulation and Inadvertent Hypothermia
- · Clinical consequences of perioperative hypothermia
- Coagulation and Postoperative Prothrombotic State
- · VTE risk stratification and prophylaxis
- Preoperative Surgical Risk Assessment
- · ASA Classification (American Society of Anesthesiologists)
- · Assessment of cardiovascular risk
- · Pulmonary risk assessment
- Preoperative Optimization of Comorbidities
- · Perioperative management of diabetes mellitus
- · Management of chronic anticoagulation (bridging)
- · Correction of preoperative anemia
- · Surgical prehabilitation
- Perioperative Fluid Therapy
- · Crystaloids vs. colloids
- · Fluid therapy strategies: restrictive vs. liberal vs. goal-directed
- · Replacement of blood loss
- Intraoperative Hemodynamic Management and Monitoring
- · Intraoperative hypotension and organ damage
- · Advanced hemodynamic monitoring
- · Management of blood pressure and vasopressors
- Postoperative Multimodal Analgesia
- · Components of multimodal analgesia
- ERAS Programs (Enhanced Recovery After Surgery)
- · Key components of an ERAS protocol
- Systemic Postoperative Complications
- · Respiratory complications
- · Kidney complications
- · Complications of the surgical wound
- · Postoperative delirium
- Postoperative Ileus and Nutritional Support
- · Perioperative nutritional support
- Postoperative Fever: The "5 W" Approach
The complete study guide is in the app
This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.
- Subject
- Surgery
- Category
- Clinical Specialties
- Type
- Study Guide
- Sections
- 52
- Reviewed
- 2026-08-02