Epistemis

Surgery: Pathophysiological Bases and Perioperative Management

Surgery · Clinical Specialties

How it begins

Estudio exhaustivo de la respuesta sistémica a la agresión quirúrgica, la evaluación y optimización del riesgo perioperatorio, y el manejo racional del paciente quirúrgico desde la valoración preoperatoria hasta la recuperación postoperatoria.

What it covers

  1. Pathophysiological Bases and Perioperative Management
  2. The Surgical Patient as a Model of Physiological Stress
  3. Metabolic Phases of the Surgical Response: Cuthbertson and Moore
  4. · Cuthbertson's two-phase model: "Ebb and Flow"
  5. Neuroendocrine Response to Surgical Aggression
  6. · Sympathetic nervous system and catecholamines
  7. · Hypothalamic-pituitary-adrenal axis
  8. Systemic Inflammatory Response to Surgical Trauma
  9. · Cytokine cascade
  10. · Acute phase proteins
  11. · SIRS and its relationship with surgical trauma
  12. Catabolism and Substrate Metabolism in the Surgical Patient
  13. · Stress hyperglycemia
  14. · Protein catabolism and nitrogen balance
  15. · Lipid metabolism
  16. Perioperative Hydroelectrolyte Balance Alterations
  17. · The "third space" phenomenon
  18. · Sodium and water retention
  19. · Potassium alterations
  20. Perioperative Thermoregulation and Inadvertent Hypothermia
  21. · Clinical consequences of perioperative hypothermia
  22. Coagulation and Postoperative Prothrombotic State
  23. · VTE risk stratification and prophylaxis
  24. Preoperative Surgical Risk Assessment
  25. · ASA Classification (American Society of Anesthesiologists)
  26. · Assessment of cardiovascular risk
  27. · Pulmonary risk assessment
  28. Preoperative Optimization of Comorbidities
  29. · Perioperative management of diabetes mellitus
  30. · Management of chronic anticoagulation (bridging)
  31. · Correction of preoperative anemia
  32. · Surgical prehabilitation
  33. Perioperative Fluid Therapy
  34. · Crystaloids vs. colloids
  35. · Fluid therapy strategies: restrictive vs. liberal vs. goal-directed
  36. · Replacement of blood loss
  37. Intraoperative Hemodynamic Management and Monitoring
  38. · Intraoperative hypotension and organ damage
  39. · Advanced hemodynamic monitoring
  40. · Management of blood pressure and vasopressors
  41. Postoperative Multimodal Analgesia
  42. · Components of multimodal analgesia
  43. ERAS Programs (Enhanced Recovery After Surgery)
  44. · Key components of an ERAS protocol
  45. Systemic Postoperative Complications
  46. · Respiratory complications
  47. · Kidney complications
  48. · Complications of the surgical wound
  49. · Postoperative delirium
  50. Postoperative Ileus and Nutritional Support
  51. · Perioperative nutritional support
  52. Postoperative Fever: The "5 W" Approach

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Surgery
Category
Clinical Specialties
Type
Study Guide
Sections
52
Reviewed
2026-08-02
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