Epistemis

Schizophrenia and Psychosis Spectrum — Psychiatry and Neurosciences

Psychiatry · Clinical Specialties

How it begins

La conceptualización de la esquizofrenia representa uno de los debates epistémicos más complejos de la medicina moderna, transitando desde los constructos unitarios del siglo XIX hasta los modelos dimensionales contemporáneos del neurodesarrollo.

What it covers

  1. Historical Evolution and Epistemology of Psychosis
  2. · The Genesis of the Construct: From Early Dementia to Schizophrenia
  3. · The Pragmatic Epistemology of Kurt Schneider
  4. · Evolution of Contemporary Classifications (DSM-5-TR and ICD-11)
  5. · Epidemiology and Demography of Psychosis
  6. Clinical Spectrum and Diagnostic Classification
  7. · Schizophrenia: Detailed Diagnostic Criteria (DSM-5-TR)
  8. · Schizophreniform Disorder
  9. · Brief Psychotic Disorder (Brief Reactive Psychosis)
  10. · Schizoaffective Disorder
  11. · Fixed Delusions Disorder (Delusional Disorder - Paranoia)
  12. · Clinical Catatonia
  13. Pathophysiology and Neurobiology of the Spectrum
  14. · Genetic Architecture and Risk Variants
  15. · Neurodevelopment Hypothesis
  16. · Aberrant Synaptic Pruning and Cortical Connectivity
  17. · Neurochemical Models of Psychosis
  18. Clinical Domains and Instruments of Psychopathology
  19. · Positive Symptoms: Hallucinations and Delusions
  20. · Formal Disorganization of Thought and Behavior
  21. · Negative Symptoms and Cognitive Deficits
  22. Structured and Instrumental Evaluation
  23. · Positive and Negative Syndromes Scale (PANSS)
  24. · Findings in Neuroimaging and Biomarkers
  25. Medical-Psychiatric Differential Diagnosis
  26. · Initial Medical Screening: Mandatory Protocol
  27. Advanced Pharmacological Treatment and Receptorlogy
  28. · Classification and Pharmacodynamics of Antipsychotics
  29. · Clozapine: The Gold Standard in Refractory Schizophrenia
  30. · Long Acting Antipsychotics (LAI)
  31. · Neuroleptic Malignant Syndrome (NMS)
  32. · Tardive Dyskinesia (TD)
  33. Non-Pharmacological and Psychosocial Interventions
  34. · Electroconvulsive Therapy (ECT) in Schizophrenia
  35. Clinical Course and Phases of Psychosis
  36. Evidence-Based Treatment Algorithms
  37. Clinical Cases of Integration and Diagnostic Pearls
  38. · Summary of Safety Objectives in Treatment

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Psychiatry
Category
Clinical Specialties
Type
Study Guide
Sections
38
Reviewed
2026-08-02
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