Infectology — Introduction and General Principles · David Aldana

Internal Medicine · Clinical Specialties

How it begins

Una aproximación integrada al estudio de las enfermedades causadas por agentes biológicos: tríada infecciosa, microbiología, patogenia, inmunidad, diagnóstico, terapia antimicrobiana y prevención.

What it covers

1. Chapter I Infectious disease as a discipline
2. · § 1.1 Definition and scope
3. · § 1.2 Brief history
4. · § 1.3 Why it matters today
5. Chapter II The host-agent-environment triad
6. · § 2.1 The classical model
7. · § 2.2 The agent
8. · § 2.3 The host
9. · § 2.4 The environment
10. Chapter III Classification of pathogenic microorganisms
11. · § 3.1 Bacteria
12. · § 3.2 Viruses
13. · § 3.3 Fungi
14. · § 3.4 Parasites
15. · § 3.5 Prions
16. Chapter IV Mechanisms of pathogenesis and virulence
17. · § 4.1 The stages of pathogenesis
18. · § 4.2 Virulence factors
19. · § 4.3 Viral mechanisms of pathogenesis
20. · § 4.4 Genetic determinants of virulence
21. Chapter V Immune response to infection
22. · § 5.1 Constitutive barriers and defenses
23. · § 5.2 Innate immunity
24. · § 5.3 Adaptive immunity
25. · § 5.4 Immunological memory
26. · § 5.5 Immunopathology and immune-mediated damage
27. Chapter VI Natural history of the infectious disease
28. · § 6.1 Classic phases
29. · § 6.2 Clinical spectrum
30. · § 6.3 Carriers
31. Chapter VII Epidemiology of infectious diseases
32. · § 7.1 The epidemiological chain
33. · § 7.2 Reservoirs
34. · § 7.3 Transmission mechanisms
35. · § 7.4 Key epidemiological measures
36. · § 7.5 Outbreaks, epidemics and pandemics
37. Chapter VIII Principles of diagnosis
38. · § 8.1 General approach
39. · § 8.2 Direct diagnosis
40. · § 8.3 Indirect diagnosis (serology)
41. · § 8.4 Molecular tests
42. · § 8.5 Interpretation: sensitivity, specificity, predictive values
43. Chapter IX Principles of antimicrobial therapy
44. · § 9.1 Basic concepts
45. · § 9.2 PK/PD: what determines effectiveness
46. · § 9.3 Action mechanisms
47. · § 9.4 Antibiotic selection
48. · § 9.5 Antimicrobial resistance
49. · § 9.6 Antimicrobial stewardship
50. Chapter X Prevention of infectious diseases
51. · § 10.1 Immunization
52. · § 10.2 Antimicrobial prophylaxis
53. · § 10.3 Infection control
54. · § 10.4 Sanitation and public health
55. Chapter XI Infections associated with health care
56. · § 11.1 Definition and magnitude
57. · § 11.2 Main types
58. · § 11.3 Prevention: bundles
59. · § 11.4 Clostridioides difficile and its special place
60. Chapter XII Emerging diseases and the One Health perspective
61. · § 12.1 Definitions
62. · § 12.2 Factors that favor emergency
63. · § 12.3 Recent examples
64. · § 12.4 One Health
65. · § 12.5 Conceptual closure
66. Selected bibliography