Epistemis

Infectology: Special Situations | Advanced Medical Reference Manual

Internal Medicine · Clinical Specialties

How it begins

Una guía de referencia avanzada para el manejo clínico, diagnóstico y farmacoterapéutico de infecciones en pacientes inmunocomprometidos, receptores de trasplantes, pacientes con VIH avanzado, y situaciones clínicas especiales (embarazo, cirrosis, disfunción renal, asplenia y sepsis de difícil control).

What it covers

  1. Pathophysiology of Immunocompromize and Infectious Susceptibility
  2. · Physiopathological Classification of Immunodeficiencies
  3. Risk Stratification, Definitions and Microbiology
  4. · Operational Definition
  5. Therapeutic Strategy, Escalation and Management of Fungal Infections
  6. · First Line Empirical Antibiotic Treatment
  7. · Persistence of Fever: Approach on Day +4 to +7
  8. Chronology of Post-Transplant Infection
  9. · Infection Risk Timeline
  10. High Impact Opportunistic Infections: CMV, EBV and BK Nephropathy
  11. · Cytomegalovirus (CMV): The Cardinal Opportunistic Pathogen
  12. · Epstein-Barr Virus (EBV) and Post-Transplant Lymphoproliferative Disorder (PTLD)
  13. Hematopoietic Stem Transplantation (HSCT)
  14. · Physiopathological Differences: Allogeneic vs. Autologous
  15. Infections Associated with Biological Therapies and Small Molecules
  16. · Key Drugs and Their Specific Infectious Risk
  17. Advanced immunosuppression, Viral Load Management and Clinical Infections
  18. · The Patient with HIV and CD4 Count 200 cells/µL
  19. Opportunistic Infections of the Central Nervous System
  20. · Meningeal cryptococcosis (Cryptococcus neoformans)
  21. · Cerebral Toxoplasmosis (Toxoplasma gondii)
  22. Opportunistic Pulmonary Infections and Disseminated Infections
  23. · Pneumocystis jirovecii pneumonia (PCP)
  24. · Tuberculosis (TB) and Mycobacterium avium Complex (MAC)
  25. Inflammatory Immune Reconstitution Syndrome (IRIS)
  26. · Clinical Classification
  27. Immunosenescence and Infections in the Elderly
  28. · The Physiology of Immunosenescence
  29. Infections in Pregnant Patients and Antimicrobials
  30. · Antimicrobial Safety in Pregnancy
  31. Infections in Cirrhotic Patients and Liver Failure
  32. · Spontaneous Bacterial Peritonitis (SBP)
  33. Dose Adjustments in Renal Failure and Peritonitis due to Peritoneal Dialysis
  34. · Calculation of Kidney Function and Principles of PK/PD
  35. · Peritonitis in Peritoneal Dialysis (PD)
  36. Infections in the Asplenic Patient and Prevention of Fulminant Sepsis
  37. · The Immunological Role of the Spleen
  38. · Immunization Protocol for Splenectomized Patients
  39. Health Care Associated Infections (HCI) and Management of Multidrug Resistance
  40. · Critical Resistance Mechanisms in Gram Negatives
  41. Cardiovascular Device Infections and Infectious Endocarditis
  42. · Infections Associated with Cardiovascular Devices (Pacemaker, ICD)
  43. · Complex Infectious Endocarditis
  44. Infections of Central Nervous System Branches and Nosocomial Meningitis
  45. · Ventriculoperitoneal shunt infections (VPD) and external drainage (EVD)
  46. Sepsis, Septic Shock and Pathophysiology of Organ Dysfunction
  47. · Screening and Evaluation Tools: qSOFA and SOFA Scale
  48. · The First Hour Measures Package (Surviving Sepsis Campaign 2021)

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Internal Medicine
Category
Clinical Specialties
Type
Study Guide
Sections
48
Reviewed
2026-08-02
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