Host-Pathogen Interaction — Microbiology

Microbiology · Basic Sciences

How it begins

La interacción huésped-patógeno es el proceso dinámico y bidireccional mediante el cual un microorganismo entra en contacto con un organismo huésped, establece una relación ecológica con él y eventualmente produce o no produce enfermedad, dependiendo del equilibrio entre los factores de virulencia del patógeno y los mecanismos de defensa del huésped.

What it covers

1. Host-Pathogen Interaction
2. Fundamental Concepts
3. · Essential Terminology
4. · The Epidemiological Triangle and its Determinants
5. Symbiosis Spectrum
6. Pathogenicity and Virulence
7. · Virulence Measures
8. · Pathogenicity Islands (PAI — Pathogenicity Islands)
9. · Horizontal Gene Transfer (THG) — Accelerated Evolution of Pathogens
10. Virulence Factors
11. · Adhesinas — Colonization and Adherence
12. · Tissue Invasion — Secretion Systems
13. Microbial Toxins
14. · Exotoxins
15. · Endotoxins — LPS (Lipopolysaccharide)
16. Immune Evasion Mechanisms
17. · Evasion of Innate Immunity
18. · Evasion of Adaptive Immunity
19. Physical and Chemical Barriers of the Host
20. Innate Immunity
21. · Pattern Recognition Receivers (PRR)
22. · The NLRP3 Inflammasome — The Innate Inflammation Platform
23. · Innate Immunity Cells
24. · Complement System — Innate Artillery
25. Adaptive Immunity
26. · Cellular Immunity — T Lymphocytes
27. · Humoral Immunity — B Lymphocytes and Antibodies
28. Infectious Cycle
29. · Incubation Period — The Hidden Time
30. Transmission and Entry Gate
31. Microbiome and Dysbiosis
32. · Functions of the Intestinal Microbiome
33. · Dysbiosis — The Unbalanced Microbiome
34. Biofilm (Biofilm)
35. · Biofilm Formation Stages
36. · Quorum Sensing (QS) — Bacterial Communication
37. · Biofilm Resistance to Antibiotics
38. Intracellular Pathogens
39. · Intracellular Survival Strategies
40. Antimicrobial Resistance
41. · Antimicrobial Resistance Mechanisms
42. · ESKAPE Pathogens — The "Fugitives" of Antibiotics
43. Chronic Infection and Latency
44. Superantigens and Toxic Shock
45. · Mechanism of Action of Superantigens
46. · Main Clinical Superantigens
47. Zoonosis and Emerging Pathogens
48. · Emergence Mechanisms of New Pathogens
49. · Main Zoonoses and Emerging Pathogens
50. Integration and Final Perspective
51. · Integrating Principles of Host-Pathogen Interaction
52. · The Future of the Fight Against Infectious Diseases
53. · Summary of Key Concepts
54. · Bibliographical References