Legal Medicine: Forensic Toxicology

Legal Medicine · Clinical Bases

How it begins

Estudio exhaustivo de los tóxicos con trascendencia médico-legal: conceptos y clasificación, toxicocinética y toxicodinámica, el diagnóstico de la intoxicación en el vivo y en el cadáver, la toma y conservación de muestras, la analítica toxicológica (cribado y confirmación), la redistribución postmortem, y el estudio monográfico de los grandes grupos de venenos —cáusticos, gases, plaguicidas, metales, alcohol,…

What it covers

1. Concept of Forensic Toxicology and Poison
2. · The three branches of toxicology
3. · The questions of forensic toxicology
4. Classification of Toxics
5. · According to the chemical nature
6. · According to the target organ (toxicodynamic criterion)
7. · According to the medical-legal etiology
8. Toxicokinetics: the Journey of the Toxic
9. · Absorption routes
10. · Distribution
11. · Metabolism (biotransformation)
12. · Elimination and quantitative concepts
13. Toxicodynamics: Mechanisms of Action
14. · Fundamental mechanisms of toxicity
15. · Dose-response relationship and thresholds
16. · Factors that modify toxicity
17. Medico-Legal Diagnosis of Intoxication
18. · Toxicological syndromes ("toxidromes")
19. Taking, Conservation and Custody of Samples
20. · Biological matrices and their value
21. · Conservation
22. Toxicological Analysis
23. · Screening methods
24. · Confirmation and quantification methods
25. · Validation and quality assurance
26. Postmortem Toxicology: Redistribution and Interpretation
27. · Postmortem redistribution (RPM)
28. · Neoformation and postmortem degradation
29. · Keys for prudent interpretation
30. Caustics: Acids and Alkalis
31. · Findings and evolution
32. Toxic Gases: Carbon Monoxide and Cyanide
33. · Carbon monoxide (CO)
34. · Cyanide (CN⁻)
35. Pesticides
36. · Organophosphates and carbamates
37. · Paraquat (bipyridyl herbicide)
38. · Anticoagulant rodenticides
39. Metals and Metalloids
40. Ethyl Alcohol and Toxic Alcohols
41. · Toxicokinetics of ethanol
42. · Clinical-legal correlation of alcohol level
43. · Toxic non-ethyl alcohols
44. Drugs of Abuse
45. Drug Poisoning
46. · Insulin and "death without a trace"
47. Chemical Submission
48. · Characteristics of the "ideal" agent for submission
49. Integrative Synthesis