Epistemis

Integrated Diagnostic Approach to Special Pathology — Epistemis

Special Pathology · Basic Sciences

How it begins

From the clinical question to the final diagnosis: sample, morphology, immunophenotype, genomics, WHO classification, stage and communication. The goal is to connect all guides per organ without converting any isolated marker into a diagnosis.

What it covers

  1. What a pathological diagnosis answers
  2. · What is it?
  3. · How does it behave?
  4. · How far does it extend?
  5. Pre-analytical phase
  6. Sampling, orientation and processing
  7. · Maximum diagnosis with minimum tissue
  8. · Reproducible anatomical map
  9. Pattern-based reading
  10. Immunohistochemistry as a panel with controls
  11. · Lineage
  12. · Origin / entity
  13. · Prediction
  14. Question-driven molecular pathology
  15. Classify, grade and stage
  16. · Which entity it is
  17. · Intrinsic aggressiveness
  18. · Anatomical extent
  19. · Therapeutic effect
  20. Integrated and synoptic report
  21. · Minimum oncology template
  22. Cytology and small biopsies
  23. · Decide whether it is sufficient
  24. · Planning from the first section
  25. Digital pathology and artificial intelligence
  26. Errors and interceptors
  27. Cross-cutting algorithms
  28. · Poorly differentiated malignant neoplasm
  29. · Metastatic adenocarcinoma of uncertain origin
  30. · Spindle cell lesion
  31. References and currency

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Special Pathology
Category
Basic Sciences
Type
Study Guide
Sections
31
Reviewed
2026-09-19
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