Psychiatry: Depressive Disorders

Psychiatry · Clinical Specialties

How it begins

Revisión clínica exhaustiva: neurobiología, fenomenología, criterios diagnósticos, evaluación del riesgo, y abordaje terapéutico farmacológico y psicoterapéutico de los trastornos depresivos en la práctica psiquiátrica.

What it covers

1. Introduction: Clinical and Epidemiological Burden
2. Neurobiology of Depression
3. · Monaminergic Hypothesis: Origin and Limitations
4. · Neuroplasticity and the Neurotrophic Hypothesis
5. · Hypothalamus-Pituitary-Adrenal (HPA) Axis and Chronic Stress
6. · Neuroinflammation
7. · Circuits and Connectivity: Beyond Monoamines
8. · Genetics and Epigenetics
9. Nosological Classification: DSM-5-TR and CIE-11
10. Major Depressive Disorder (MDD): DSM-5-TR Diagnostic Criteria
11. · Gravity Specifier
12. Clinical Specifiers of the Depressive Episode
13. Persistent Depressive Disorder (Dysthymia)
14. Differential Diagnosis
15. · Differentiation with Bipolar Disorder
16. · Medical and Pharmacological Causes of Depressive Symptoms
17. · Other Psychiatric Differential Diagnoses
18. Systematic Clinical Evaluation
19. · Structured Psychiatric History
20. · Mental State Exploration
21. Suicidal Risk Assessment
22. · Evaluation Framework: From Thought to Behavior
23. · Risk Factors
24. · Protective Factors
25. · Security Planning
26. · Level of Care Decision
27. Clinical Evaluation Scales
28. Pharmacological Treatment
29. · General Principles
30. · Selective Serotonin Reuptake Inhibitors (SSRIs) — First Line
31. · Other First/Second Line Antidepressants
32. · Tricyclic antidepressants (TCA) and MAOIs
33. · Serotonin Syndrome and Discontinuation Syndrome
34. · Potentiation and Combination in Partial Response
35. Evidence-Based Psychotherapy
36. Treatment Resistant Depression
37. · Approach Algorithm for Inadequate Response
38. · Biomarkers and Precision Medicine
39. Neurostimulation Therapies
40. Considerations in Special Populations
41. · Perinatal Depression
42. · Depression in the Elderly
43. · Depression in Children and Adolescents
44. · Depression and Chronic Medical Comorbidity