Psychiatry: Trauma and Stress Factors | Neurobiology and Clinical Treaty
Psychiatry · Clinical Specialties
How it begins
Un tratado exhaustivo y de nivel de subespecialidad sobre la fisiopatología, diagnóstico multidimensional y abordaje psicofarmacológico y psicoterapéutico de los trastornos relacionados con el trauma y factores de estrés según el DSM-5-TR y la CIE-11.
What it covers
- Epistemology and Classification of Trauma-Related Disorders
- · Criterion A as an Etiological Threshold
- Neurobiology of the HPA Axis and Corticolimbic Structures
- · The Hypothalamic-Pituitary-Adrenal (HPA) Axis: Paradoxical Hypocortisolemia
- · Corticolimbic Dysfunction: Amygdala, Hippocampus and PFC
- Epigenetics, Allostasis and Allostatic Load
- · Epigenetic Mechanisms in Trauma
- · Allostasis and Allostatic Load: The Bruce McEwen Model
- Genetics of Vulnerability and Resilience to Stress
- · Gene-Environment Interactions (GxE)
- Post-Traumatic Stress Disorder (PTSD): DSM-5-TR Diagnostic Criteria
- · The Four Symptom Domains of PTSD (Criteria B to E)
- · Diagnostic Comparison: DSM-5-TR vs. ICD-11 (WHO)
- PTSD with Dissociative Symptoms: The Neurobiological Subtype
- · Differential Neurobiology of the Dissociative Subtype
- Complex Posttraumatic Stress Disorder (C-PTSD) in the ICD-11
- · The ICD-11 Structure for C-PTSD
- Acute Stress Disorder (ASD): Pathophysiology and Transition to Chronicity
- · Diagnostic Criteria (DSM-5-TR)
- · Pathophysiology of Traumatic Memory Consolidation
- Adjustment Disorders: Classification and Clinical Approach
- · Diagnostic Criteria and Specifiers in the DSM-5-TR
- · Clinical Approach and Avoidance of Medicalization
- Attachment Disorders: Reactive Attachment (TAR) and Disinhibited Social Relationship (TRSD)
- · Reactive Attachment Disorder (RAD): The Internalizing Phenotype
- · Disinhibited Social Relationship Disorder (TRSD): The Externalizing Phenotype
- Psychopathology and Neuroscience of Dissociation
- · The Default Neural Network (DMN) and the Salience Network (SN)
- Childhood Trauma, Neurodevelopment and the ACE Study (Adverse Childhood Experiences)
- · ACE Categories and Their Dose-Response Correlation
- Immunopsychiatry of Trauma: Cytokines and the Microbiota-Gut-Brain Axis
- · Microglial Activation and Neuroinflammation
- · The Microbiota-Gut-Brain Axis under Traumatic Stress
- Somatization, Chronic Pain, and Trauma-Related Somatic Symptom Disorders
- · Pathophysiology of Central Sensitization and Allodynia
- Multidimensional Differential Diagnosis of Trauma
- · Key Diagnostic Frontiers
- Psychometric Methods and Structured Clinical Evaluation
- · First Line Psychometric Scales
- Trauma Psychopharmacology: First Line Agents and Symptomatic Modulation
- · Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin and Noradrenaline Inhibitors (SNRIs)
- · Treatment of Traumatic Insomnia and Nightmares: Prazosin
- Emerging Psychopharmacology and Translational Psychiatry
- · Glutamatergic Modulation Agents: Ketamine and Esketamine
- · Assisted Psychotherapy with MDMA (3,4-methylenedioxymethamphetamine)
- · Pharmacology of Memory Reconsolidation: Propranolol
- Evidence-Based First-Line Psychotherapies
- · 1. Eye Movement Desensitization and Reprocessing (EMDR)
- · 2. Prolonged Exposure Psychotherapy (PE)
- · 3. Cognitive Processing Therapy (CPT)
- Emergency Management, Suicide Prevention and Therapeutic Algorithm
- · Evaluation of the Risk of Suicide in the Traumatized Patient
The complete study guide is in the app
This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.
- Subject
- Psychiatry
- Category
- Clinical Specialties
- Type
- Study Guide
- Sections
- 52
- Reviewed
- 2026-08-02