Epistemis

Psychiatry: Trauma and Stress Factors | Neurobiology and Clinical Treaty

Psychiatry · Clinical Specialties

How it begins

Un tratado exhaustivo y de nivel de subespecialidad sobre la fisiopatología, diagnóstico multidimensional y abordaje psicofarmacológico y psicoterapéutico de los trastornos relacionados con el trauma y factores de estrés según el DSM-5-TR y la CIE-11.

What it covers

  1. Epistemology and Classification of Trauma-Related Disorders
  2. · Criterion A as an Etiological Threshold
  3. Neurobiology of the HPA Axis and Corticolimbic Structures
  4. · The Hypothalamic-Pituitary-Adrenal (HPA) Axis: Paradoxical Hypocortisolemia
  5. · Corticolimbic Dysfunction: Amygdala, Hippocampus and PFC
  6. Epigenetics, Allostasis and Allostatic Load
  7. · Epigenetic Mechanisms in Trauma
  8. · Allostasis and Allostatic Load: The Bruce McEwen Model
  9. Genetics of Vulnerability and Resilience to Stress
  10. · Gene-Environment Interactions (GxE)
  11. Post-Traumatic Stress Disorder (PTSD): DSM-5-TR Diagnostic Criteria
  12. · The Four Symptom Domains of PTSD (Criteria B to E)
  13. · Diagnostic Comparison: DSM-5-TR vs. ICD-11 (WHO)
  14. PTSD with Dissociative Symptoms: The Neurobiological Subtype
  15. · Differential Neurobiology of the Dissociative Subtype
  16. Complex Posttraumatic Stress Disorder (C-PTSD) in the ICD-11
  17. · The ICD-11 Structure for C-PTSD
  18. Acute Stress Disorder (ASD): Pathophysiology and Transition to Chronicity
  19. · Diagnostic Criteria (DSM-5-TR)
  20. · Pathophysiology of Traumatic Memory Consolidation
  21. Adjustment Disorders: Classification and Clinical Approach
  22. · Diagnostic Criteria and Specifiers in the DSM-5-TR
  23. · Clinical Approach and Avoidance of Medicalization
  24. Attachment Disorders: Reactive Attachment (TAR) and Disinhibited Social Relationship (TRSD)
  25. · Reactive Attachment Disorder (RAD): The Internalizing Phenotype
  26. · Disinhibited Social Relationship Disorder (TRSD): The Externalizing Phenotype
  27. Psychopathology and Neuroscience of Dissociation
  28. · The Default Neural Network (DMN) and the Salience Network (SN)
  29. Childhood Trauma, Neurodevelopment and the ACE Study (Adverse Childhood Experiences)
  30. · ACE Categories and Their Dose-Response Correlation
  31. Immunopsychiatry of Trauma: Cytokines and the Microbiota-Gut-Brain Axis
  32. · Microglial Activation and Neuroinflammation
  33. · The Microbiota-Gut-Brain Axis under Traumatic Stress
  34. Somatization, Chronic Pain, and Trauma-Related Somatic Symptom Disorders
  35. · Pathophysiology of Central Sensitization and Allodynia
  36. Multidimensional Differential Diagnosis of Trauma
  37. · Key Diagnostic Frontiers
  38. Psychometric Methods and Structured Clinical Evaluation
  39. · First Line Psychometric Scales
  40. Trauma Psychopharmacology: First Line Agents and Symptomatic Modulation
  41. · Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin and Noradrenaline Inhibitors (SNRIs)
  42. · Treatment of Traumatic Insomnia and Nightmares: Prazosin
  43. Emerging Psychopharmacology and Translational Psychiatry
  44. · Glutamatergic Modulation Agents: Ketamine and Esketamine
  45. · Assisted Psychotherapy with MDMA (3,4-methylenedioxymethamphetamine)
  46. · Pharmacology of Memory Reconsolidation: Propranolol
  47. Evidence-Based First-Line Psychotherapies
  48. · 1. Eye Movement Desensitization and Reprocessing (EMDR)
  49. · 2. Prolonged Exposure Psychotherapy (PE)
  50. · 3. Cognitive Processing Therapy (CPT)
  51. Emergency Management, Suicide Prevention and Therapeutic Algorithm
  52. · Evaluation of the Risk of Suicide in the Traumatized Patient

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Psychiatry
Category
Clinical Specialties
Type
Study Guide
Sections
52
Reviewed
2026-08-02
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