Epistemis

Addictive Substances and Disorders — Psychiatry and Clinical Neurobiology

Psychiatry · Clinical Specialties

How it begins

La psiquiatría de las adicciones ha transitado desde un enfoque moral y de desviación conductual hacia un modelo neurobiológico integral basado en la conceptualización de las conductas adictivas como trastornos crónicos y recurrentes del cerebro.

What it covers

  1. Concept, Epidemiology and Socio-health Impact
  2. · Definition and Conceptual Delimitation
  3. · Global Epidemiology and Disease Burden
  4. Neurobiology of Addiction: Circuits and Neurotransmission
  5. · The Mesocorticolimbic Reward Circuit
  6. · Synaptic and Epigenetic Neuroplasticity
  7. · Allostasis and the Brain Stress System: The Three Phase Model
  8. Diagnosis and Taxonomic Classification
  9. · DSM-5-TR and ICD-11 Diagnostic Criteria
  10. · Psychiatric Comorbidity and Dual Pathology
  11. Alcohol Use Disorder and Withdrawal Syndromes
  12. · Physiopathology and Neurochemistry of Ethanol
  13. · Delirium Tremens and Wernicke's Encephalopathy
  14. · Maintenance and Discontinuation Pharmacotherapy
  15. Opioids and Substitution Treatment / Detoxification
  16. · Opioid Receptors and Signaling Mechanisms
  17. · Clinical Picture: Overdose and Withdrawal
  18. · Substitution Treatments (MOUD)
  19. Stimulants: Cocaine, Amphetamines and Psychotic Symptoms
  20. · Cocaine: Mechanisms of Action and Organic Toxicity
  21. · Amphetamines, Methamphetamine and Synthetic Derivatives
  22. · Excited Delirium Syndrome
  23. Cannabis and Hallucinogens
  24. · The Endocannabinoid System and Δ9-THC
  25. · Classic and Dissociative Hallucinogens
  26. Sedatives, Hypnotics and Anxiolytics
  27. · Pharmacological Differences: Benzodiazepines vs. Barbiturates
  28. · Withdrawal Syndrome and Gradual Withdrawal Protocol
  29. Nicotine, Inhalants and Inhalants
  30. · Nicotine Receptors and Discontinuation Pharmacotherapy
  31. · Inhalants and Inhalants: Volatile Solvents
  32. Addictive Disorders Not Related to Substances (Behavioral Addictions)
  33. · Pathological Gambling (Pathological Gambling)
  34. · Video Game and New Technology Use Disorder
  35. Complex Clinical Cases and Psychiatric Pearls
  36. · Clinical Cases of Psychiatric Integration
  37. · High Performance Psychiatric Pearls
  38. · Table of Differential Diagnosis of Acute Intoxication
  39. · Summary of Dishabituation Objectives and Therapeutic Algorithm

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Psychiatry
Category
Clinical Specialties
Type
Study Guide
Sections
39
Reviewed
2026-08-02
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