Hemostasis and Coagulation Disorders

Hemostasis and Coagulation Disorders — Internal Medicine

How it begins

Análisis exhaustivo de la fisiología de la hemostasia, el diagnóstico diferencial de las diátesis hemorrágicas y trombóticas, y el manejo clínico avanzado de cada entidad con base en la evidencia contemporánea.

What it covers

1. Hemostasis and Coagulation Disorders
2. Physiology of Hemostasis — The Three-Phase System
3. · Primary hemostasis — Platelet plug formation
4. The Coagulation Cascade — Contemporary Cellular Model
5. · Cellular model of coagulation — Three phases
6. · Fibrin clot formation and consolidation
7. · Natural anticoagulants — Brake system
8. Fibrinolysis — Clot Removal System
9. Laboratory Tests of Hemostasis — Expert Interpretation
10. · Front-line tests
11. · Interpretation of laboratory patterns
12. Immune Thrombocytopenic Purpura (ITP)
13. · Temporal classification
14. · Treatment by lines — ASH Guidelines 2019
15. Heparin-Induced Thrombocytopenia (HIT)
16. · Score 4T — Pretest probability of HIT
17. Thrombotic Thrombocytopenic Purpura (TTP) and Hemolytic Uremic Syndrome (HUS)
18. Other Clinically Relevant Thrombocytopenias
19. Qualitative Platelet Disorders — Bernard-Soulier and Glanzmann
20. Von Willebrand Disease (VWD) — The Most Common Coagulopathy
21. Hemophilia A and B — X-Linked Coagulopathies
22. · Clinical manifestations
23. · Treatment — Era of extended half-life (EHL) agents
24. Other Rare Hereditary Coagulopathies
25. Disseminated Intravascular Coagulation (DIC)
26. · Main causes of DIC
27. · DIC diagnostic score (ISTH 2001) — for overt DIC
28. Hepatic Coagulopathy — The Hemostatic Rebalance Paradigm
29. Management of Bleeding due to Anticoagulants
30. Hereditary Thrombophilias — Epidemiology and Clinical Risk
31. Antiphospholipid Syndrome (APS) — Prototypical Acquired Thrombophilia
32. · Sapporo classification criteria (revised 2006)
33. · Catastrophic SAF (CAPS) — The emergency of the SAF
34. Venous Thromboembolism (VTE) — Diagnosis and Treatment
35. · Wells Score for DVT and PE — Pretest Probability
36. · Severity stratification of PE — ESC 2019 Model
37. · Duration of anticoagulation in VTE