Epistemis

Pigmentation Disorders — Medical Dermatology

Dermatology · Clinical Specialties

How it begins

Análisis exhaustivo de los mecanismos moleculares de la melanogénesis, las alteraciones congénitas y adquiridas de la pigmentación, su fisiopatología, diagnóstico diferencial y opciones terapéuticas actuales.

What it covers

  1. Biology of the Melanocyte and the Epidermal Unit of Melanization
  2. · Origin in the Neural Crest and Cellular Specification
  3. · Structure of the Mature Melanocyte
  4. · Types of Melanin and Determinants of Phototype
  5. Melanogenesis: Biochemistry and Biogenesis of Melanosomes
  6. · The Biochemical Pathway of Melanogenesis
  7. · Biogenesis of Melanosomes: The Four Stages
  8. · Hormonal and Environmental Regulation of Melanogenesis
  9. General Classification of Pigmentation Disorders
  10. Vitiligo
  11. · Pathophysiology: The Autoimmune Model
  12. · Genetics of Vitiligo
  13. · Clinical Classification of Vitiligo
  14. · Diagnosis
  15. Albinism: Types, Genetics and Systemic Manifestations
  16. · Oculocutaneous Albinism (OCA): Seven Types
  17. · Ocular Manifestations of Albinism
  18. · Albinism Syndromes with Systemic Commitment
  19. · Dermatological Management of Albinism
  20. Other Relevant Hypopigmentations
  21. Melasma (Chloasma)
  22. · Pathophysiology of Melasma
  23. · Depth Classification
  24. Ephelides, Lentigo and Coffee with Milk Spots
  25. Post-Inflammatory Hyperpigmentation (PIH)
  26. · Physiopathological Mechanism
  27. · Treatment of PIH
  28. Other Relevant Acquired Hyperpigmentation
  29. Hyperpigmentation of Systemic and Endocrine Origin
  30. · Addison's Disease (Primary Adrenal Insufficiency)
  31. · Cushing's Syndrome and Paradoxical Pigmentation
  32. · Argyria, Chrysoderma and Exogenous Pigmentations
  33. Melanocytic Nevi: Classification, Molecular Biology and Risk of Melanoma
  34. · Histological Classification
  35. · Molecular Biology of Melanocytic Transformation
  36. Depigmentation Treatments: Comparative Mechanisms of Action
  37. Integrating Differential Diagnosis and Diagnostic Tools
  38. · Essential Diagnostic Tools
  39. · Algorithm for Differential Diagnosis of Hypopigmented Lesions
  40. · Algorithm for Differential Diagnosis of Facial Hyperpigmented Lesions

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Dermatology
Category
Clinical Specialties
Type
Study Guide
Sections
40
Reviewed
2026-08-02
Download Epistemis