Treatise on Prostate Pathology and Surgery — Specialization in Urology

Surgery · Clinical Specialties

How it begins

Un compendio exhaustivo y de alta especialización quirúrgica para el urólogo moderno. Aborda con máximo rigor la anatomía zonal de McNeal, la fisiopatología celular de la hiperplasia y la carcinogénesis, el estadiaje por resonancia multiparamétrica y PET-PSMA, así como la descripción minuciosa paso a paso de la prostatectomía radical asistida por robot (RARP), técnicas de enucleación con láser (HoLEP) y terapias…

What it covers

1. McNeal Zonal Segmentation and Functional Histology
2. Vascularization, Aponeurotic Compartments and Cavernous Nerves
3. · Prostatic Vascularization: Pedicles and Fine Irrigation
4. · Fascial Planes of the Male Pelvis
5. Cellular, Hormonal and Stromal Physiopathology of BPH
6. · The Androgenic Pathway and the Role of Dihydrotestosterone (DHT)
7. · The Reciprocal Stroma-Epithelium Interaction and Growth Factors
8. Lower Urinary Tract Symptoms (LUTS/LUTS) and Diagnosis
9. · Physiopathology of Obstruction: Static Component vs. Dynamic
10. · Objective Diagnostic Strategies
11. Adjuvant Pharmacotherapy of BPH: Mechanisms and Clinical Trials
12. · 1. Alpha-1 Adrenergic Receptor Blockers (-blockers)
13. · 2. 5-alpha-reductase Enzyme Inhibitors (5ARIs)
14. · 3. High Evidence Combination Therapy (-blocker + 5ARI)
15. Transurethral Resection of the Prostate (TURP) Monopolar and Bipolar
16. · Technical Differences: Monopolar TURP vs. Bipolar
17. Open Prostatic Adenomectomy: Freyer and Millin Techniques
18. · 1. Transvesical Adenomectomy (Freyer Technique)
19. · 2. Extravesical Retropubic Adenomectomy (Millin Technique)
20. Laser Prostatic Enucleation: HoLEP and ThuLEP
21. · Biophysics of Laser Systems
22. · HoLEP Surgical Technique (Holmium Laser Enucleation of the Prostate)
23. New Minimally Invasive Technologies (MIST): Rezūm, Aquablation and Urolift
24. · 1. Thermal Therapy with Water Vapor (Rezūm)
25. · 2. Robotic Hydroablation by Water Jet (Aquablation)
26. · 3. Tensile Intraprostatic Staples (Urolift)
27. Molecular Biology of Carcinogenesis and PSA Controversies
28. · Molecular Basis of Prostatic Oncogenesis
29. · Fine Kinetics and Clinical Limitations of Prostate Specific Antigen (PSA)
30. Gleason and ISUP Histological Staging, and Fusion Biopsy
31. · The Gleason and ISUP Grading System
32. · MRI-Ultrasound Fusion Biopsy
33. Advanced Staging: mpMRI (PI-RADS v2.1) and PSMA Tomography
34. · Multiparametric Magnetic Resonance (mpMRI) of the Prostate
35. · Positron Emission Tomography (PET/CT) directed against PSMA
36. Robot-Assisted Radical Prostatectomy: Step-by-Step Technique
37. · Arrangement of Access Ports and Patient Positioning
38. · RARP Surgical Technique Step by Step
39. Continence Preservation Techniques and Van Velthoven Anastomosis
40. · 1. Posterior Reconstruction of the Sphincter (Rocco's Point)
41. · 2. Watertight Urethrovesical Anastomosis (Van Velthoven Technique)
42. Extended Pelvic Lymphadenectomy vs. Limited
43. · Anatomical Differences: Limited Lymphadenectomy vs. Extended
44. Management of Biochemical Recurrence and Salvage Therapies
45. · Definition of Biochemical Recurrence (BCR)
46. · Differential Diagnosis: Local Recurrence vs. Systemic (Metastatic)
47. Prostatitis and Chronic Pelvic Pain Syndrome
48. · NIH Classification of Prostatitis Syndromes
49. Clinical Management Protocols and Surgical Decision Making
50. · BPH Treatment Selection Algorithm (Based on Patient Size and Desire)