Toxicological Emergencies

Toxicological Emergencies — Expert Level Reference

How it begins

Guía de referencia de nivel experto para el abordaje celular, diagnóstico analítico, monitorización electrofisiológica y terapéutica antidótica avanzada de los síndromes toxicológicos críticos en la medicina de urgencias.

What it covers

1. Initial assessment of the intoxicated patient and characterization of toxidromes
2. · Systematic characterization of cardinal toxidromes
3. Gastrointestinal decontamination and extracorporeal purification techniques
4. · 1. Activated Charcoal in Single Dose (CADU)
5. · 2. Gastric lavage
6. · 3. Total Intestinal Irrigation (TII)
7. · 4. Activated Charcoal in Multiple Doses (CADM)
8. · 5. Extracorporeal Cleansing Techniques
9. Paracetamol (Acetaminophen) Poisoning
10. · Cellular Pathophysiology and NAPQI Formation
11. · Clinical Phases of Hepatotoxicity
12. · Diagnostic Evaluation: Rumack-Matthew Nomogram
13. · Treatment Schemes with N-Acetylcysteine (NAC)
14. · King's College Criteria for Urgent Liver Transplantation
15. Salicylate Poisoning (Acetylsalicylic Acid)
16. · Cellular Pathophysiology and Uncoupling of Oxidative Phosphorylation
17. · Acid-Base Balance Disorders
18. · Clinical Manifestations and Neurotoxicity
19. · Therapeutic Approach and Risks of Intubation
20. Cardiovascular Toxins: Beta-blockers and Calcium Antagonists
21. · Pathophysiology of Beta-blocker Intoxication
22. · Pathophysiology of Calcium Antagonist Intoxication
23. · Stepped Therapeutic Approach and HIET Therapy
24. Digoxin and Cardiotonic Glycosides
25. · Cellular Pathophysiology and Electrical Conduction
26. · Clinical Manifestations: Acute vs. Chronic Intoxication
27. · Electrocardiographic Findings
28. · Antidotic Therapeutics: Specific Antibodies against Digoxin (Fab)
29. Tricyclic Antidepressants (TCA)
30. · Mechanism of Action of Multisystem Toxicity
31. · Prognostic Electrocardiographic Criteria
32. · Use of 8.4% Baking Soda
33. Neuromuscular Syndromes: Serotonergic vs Neuroleptic Malignant Syndrome
34. · Serotonin Syndrome: Hunter Diagnostic Criteria
35. · Neuroleptic Malignant Syndrome (NMS)
36. · Clinical and Therapeutic Differentiation
37. Toxic Alcohols: Methanol and Ethylene Glycol
38. · 1. Pathophysiology of Methanol Intoxication
39. · 2. Pathophysiology of Ethylene Glycol Poisoning
40. · 3. Gap Calculation: Anion Gap and Osmolar Gap
41. · 4. Antidotic and Purification Therapeutic Approach
42. Carbon Monoxide and Cyanide
43. · 1. Carbon Monoxide Poisoning
44. · 2. Cyanide Poisoning
45. Acetylcholinesterase Inhibitors: Organophosphates and Carbamates
46. · Cellular Physiopathology and the Phenomenon of "Aging"
47. · Clinical Manifestations: Acute Cholinergic Toxidrome
48. · Antidotic Treatment Scheme
49. Corrosive Substances, Caustics and Heavy Metals
50. · 1. Caustic Poisoning: Acids vs. Alkalis
51. · 2. Heavy Metal Poisoning and Chelation Therapy
52. · Synthesis of Critical Toxicological Reasoning