Epistemis

USMLE Step 1: Cardiovascular Physiology, Pathophysiology and Pharmacology — Simulator and Clinical Calculators

Internal Medicine · Clinical Specialties

How it begins

Un compendio exhaustivo y un simulador interactivo de alta fidelidad clínica diseñados específicamente para dominar la dinámica de fluidos, la electrofisiología miocárdica y la terapéutica cardiovascular evaluadas en los exámenes de licenciamiento médico de EE.UU.

What it covers

  1. Cardiac Embryonic Development
  2. Congenital Heart Anomalies
  3. · 1. Left to Right Shorts (Not Initially Cyanotic)
  4. · 2. Right to Left Short Circuits (Early Cyanosis)
  5. Vascular Histology and Coronary Anatomy
  6. · 1. Coronary Dominance and Irrigation Territories
  7. · 2. Histology of the Vascular Layers
  8. Cardiac Cycle and Pressure-Volume Curves
  9. · Mechanical Phases of the Cardiac Cycle
  10. Blood Pressure Regulation and Flow Dynamics
  11. · Blood Pressure Reflex Control Systems
  12. Cardiac Output and Oxygen Transport
  13. · Determinants of Stroke Volume (Stroke Volume, SV)
  14. Cardiac Action Potentials
  15. Advanced Interpretation of Electrocardiography
  16. · Interval Analysis and Its Physiological Meaning
  17. High Performance Channelopathies and Arrhythmias
  18. · Wolff-Parkinson-White (WPW) syndrome
  19. Acute and Chronic Ischemic Heart Disease
  20. Valvular Pathophysiology and Murmur Dynamics
  21. Heart Failure and Cardiomyopathies
  22. · Comparative pathophysiology of cardiomyopathies
  23. Pericardium, Endocardium and Infectious Pathology
  24. · Acute Rheumatic Fever vs. Chronic Rheumatic Heart Disease
  25. Hemodynamic and Hypertensive Pharmacotherapy
  26. Antiarrhythmic Therapeutics: Vaughan Williams Classification
  27. Antithrombotic and Anticoagulant Pharmacology
  28. Clinical Physiology and Cardiovascular Risk Calculators
  29. · 1. Cardiac Output by Fick's Principle and Cardiac Index ($CO / CI$)
  30. · 2. Systemic Vascular Resistance ($SVR$) and Pulmonary Resistance ($PVR$)
  31. · 3. Corrected QT Interval ($QTc$) - Bazett, Fridericia and Framingham
  32. · 4. Aortic Valve Area ($AVA$) by Continuity Equation
  33. · 5. CHA₂DS₂-VASc Risk Scale for Atrial Fibrillation
  34. Interactive Cardiology Questions Simulator (USMLE QBank)

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Internal Medicine
Category
Clinical Specialties
Type
Study Guide
Sections
34
Reviewed
2026-08-02
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