Epistemis

Non-suicidal self-harm

Specialty: Psychiatry.

  • Non-suicidal self-harm
  • cutting
  • superficial affect-regulating self-mutilation

Why it occurs

  • Borderline personality disorder (BPD)
  • Major depressive disorder in adolescents
  • Post-traumatic stress disorder (PTSD)
  • Autism spectrum disorder (especially stereotypical self-mutilations such as hitting the head or biting)
  • Dissociative identity disorder
  • Lesch-Nyhan syndrome (rare metabolic cause)

Initial workup

Psychiatric evaluation of the lethality and intentionality of the act; detailed physical examination of typically hidden body areas (thighs, abdomen, inner arms); analysis with coagulation profile if there is persistent bleeding.

red flags

Escalation in the physical severity of the injuries that endangers main vascular structures (deep cuts in the wrist/forearm), severe bacterial superinfection of the wounds, or transmutation of self-injurious behavior into a real lethal autolytic attempt due to failure of the regulatory function of the cut.

Standard management

  • Naltrexone — opioid antagonist that blocks the release of endorphins that the patient seeks with physical pain to relieve emotional pain, reducing the urge to self-harm
  • Aripiprazole or Risperidone at low doses — to reduce impulsivity and emotional reactivity
  • Lamotrigine — as an affect stabilizer in BPD
  • Sertraline (to treat anxious/depressive comorbidity).

Educational guidance for study. It is NOT a prescription recommendation. The actual choice depends on the cause, the patient, and current guidelines.

Area
Psychiatry
Listed causes
6
Treatment options
4
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