Dactylitis
Specialty: Musculoskeletal.
Why it occurs
- Psoriatic arthritis (more classic association due to combined entheseal and synovial inflammation)
- Seronegative spondyloarthritis (including ankylosing spondylitis and reactive arthritis)
- Tophaceous gout or acute pseudogout
- Infectious flexor tenosynovitis (surgical emergency)
- Sarcoidosis (lupus or sarcoid dactylitis)
- Vaso-occlusive crisis due to sickle cell anemia (common in infants)
Initial workup
High resolution musculoskeletal ultrasound with Power Doppler (assesses flexor tenosynovitis, enthesitis and hydrarthrosis) | Plain radiography in AP and oblique projections of hands/feet | Acute phase reactants (CRP, ESR) | Immunological screening (Rheumatoid factor, anti-CCP antibodies, HLA-B27).
red flags
Intense erythema with lancinating pain and absolute inability to actively flex the finger, fever, history of a puncture wound on the palmar aspect (infectious suppurative tenosynovitis; risk of tendon necrosis).
Standard management
- Indomethacin — 50-75 mg every 12 hours orally; High potency non-steroidal anti-inflammatory for inflammatory crises
- Methotrexate — 15-25 mg subcutaneously once a week, associated with folic acid, for background systemic management
- Adalimumab — 40 mg subcutaneous every 14 days; anti-TNF therapy for refractory dactylitis in psoriatic arthritis
- Cefazolin (1-2 g IV every 8 hours in case of documented pyogenic infectious etiology).
Educational guidance for study. It is NOT a prescription recommendation. The actual choice depends on the cause, the patient, and current guidelines.
- Area
- Musculoskeletal
- Listed causes
- 6
- Treatment options
- 4