Epistemis

Sacroiliac pain

Specialty: Musculoskeletal.

  • sacroiliitis
  • sacroiliac joint pain
  • inflammatory buttock pain

Why it occurs

  • Inflammatory sacroiliitis in the spectrum of axial spondyloarthritis
  • Mechanical dysfunction of the sacroiliac joint (overload due to pregnancy, childbirth or limb dysmetria)
  • Pyogenic infection of the sacroiliac joint (infectious sacroiliitis, common in IV drug users or post-procedures)
  • Osteoarthritis of the sacroiliac joint due to advanced age
  • Overload secondary to previous lumbar spinal fusion

Initial workup

Magnetic resonance of sacroiliac joints with STIR sequences (early identifies active subchondral bone edema) | AP plain radiograph of the pelvis (classification of sacroiliitis according to modified New York criteria) | HLA-B27 | Quantitative CRP and ESR.

red flags

Exquisite unilateral pain in the buttock with high fever, chills, absolute inability to support the ipsilateral limb and a marked increase in acute phase reactants (suggests septic sacroiliitis, requires urgent drainage and antibiotic therapy).

Standard management

  • Indomethacin — 75 mg extended release every 12 or 24 hours orally
  • Certolizumab pegol — 200 mg subcutaneous biweekly; Biological anti-TNF therapy indicated in non-radiographic or refractory radiographic inflammatory sacroiliitis
  • Ultrasound-guided sacroiliac infiltration of triamcinolone acetonide (40 mg combined with local anesthetic).

Educational guidance for study. It is NOT a prescription recommendation. The actual choice depends on the cause, the patient, and current guidelines.

Area
Musculoskeletal
Listed causes
5
Treatment options
3
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