Vesicovaginal fistula
Specialty: Gynecology and breast.
Why it occurs
- Inadvertent surgical injury to the bladder or ureter during an abdominal or laparoscopic hysterectomy (most common benign cause in developed countries)
- Prolonged obstructed labor with pressure necrosis of the vesicovaginal tissues (more common cause in developing countries)
- Sequela due to deferred pelvic radiotherapy
- Locally advanced carcinoma of the cervix or vagina
Initial workup
Vaginal physical examination with speculum (you can observe urine output or the fistulous orifice). Bladder filling test with methylene blue (dye is instilled into the bladder through a Foley catheter and it is observed if it stains a vaginal gauze; if it does not stain but there is leakage, suspect ureterovaginal fistula). Cystoscopy and computed tomography urography (Uro-CT) to specify the exact location of the fistula and rule out associated ureteral injuries.
red flags
Constant, involuntary and uninterrupted loss of urine that begins a few days or weeks after major gynecological surgery, severe unilateral low back pain (suggestive of ureteral ligation or fistula concomitant with hydronephrosis), fever, oliguria or apparent anuria due to total loss of urine vaginally.
Standard management
- There are no drugs that close large established vesicovaginal fistulas. In very small fistulas detected early, spontaneous closure can be attempted by continuous bladder catheterization with a Foley catheter for 4-6 weeks associated with antibiotic prophylaxis with Nitrofurantoin 100 mg orally daily. The definitive treatment is surgical closure (vaginal or laparoscopic) after a few months to allow the resolution of the initial tissue inflammatory process (note: maintain abundant hydration to avoid urinary infections).
Educational guidance for study. It is NOT a prescription recommendation. The actual choice depends on the cause, the patient, and current guidelines.
- Area
- Gynecology and breast
- Listed causes
- 4
- Treatment options
- 1