Epistemis

Genu valgus or varus of progressive establishment

Specialty: Musculoskeletal.

  • joint misalignment of the lower limb
  • "X" or "O" deformity of knees

Why it occurs

  • Advanced asymmetric unicompartmental osteoarthritis of the knee (external compartment in genu valgus, internal compartment in genu varus)
  • Paget's disease of bone with deformity of the femur or tibia
  • Osteomalacia or rickets in adults due to severe vitamin D deficiency
  • Destructive rheumatoid arthritis with collapse of the lateral tibial plateau
  • Sequela of knee joint fracture consolidated in malposition (malunion of tibial plateau)
  • Avascular necrosis of the internal femoral condyle

Initial workup

Telemetry of lower limbs in weight bearing (panoramic radiography of complete legs to trace the femoro-tibial mechanical axis) | Magnetic resonance imaging of the knee (evaluates the status of the joint compartments, collateral ligaments and meniscus integrity) | General analysis to assess calcium metabolism (calcium, phosphorus, alkaline phosphatase, 25-OH-vitamin D).

red flags

Valgus or varus knee deformity that progresses rapidly in a few months associated with intractable nocturnal bone pain and a palpable mass in the distal femur or proximal tibia (suspected osteosarcoma or chondrosarcoma).

Standard management

  • There are no drugs to correct deviations of the anatomical bone axis — requires corrective osteotomy or arthroplasty); for symptomatic relief of the overloaded compartment: Chondroitin sulfate (800 mg daily orally
  • Meloxicam — 15 mg per day orally during pain attacks due to mechanical overload
  • Glucosamine sulfate (1500 mg once a day).

Educational guidance for study. It is NOT a prescription recommendation. The actual choice depends on the cause, the patient, and current guidelines.

Area
Musculoskeletal
Listed causes
6
Treatment options
3
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