Epistemis

Arnold's Neuralgia

Specialty: Neurology.

  • occipital neuralgia
  • Arnold's pain
  • greater occipital nerve entrapment

Why it occurs

  • Entrapment or irritation of the greater occipital nerve (dorsal branch of C2) as it passes through the trapezius or semispinalis capitis muscle
  • C1-C2 facet osteoarthritis or upper cervical instability
  • Sustained muscle spasm or severe contracture of the suboccipital muscles
  • Cervical trauma due to whiplash mechanism
  • Local tumors of the base of the skull or the upper cervical region

Initial workup

Selective painful palpation at Arnold's point (emergence of the occipital nerve in the superior nuchal line) that reproduces lancinating pain towards the cranial vertex; dynamic x-rays of the cervical spine to assess instability; MRI of the upper cervical spine and skull base if the pain persists or presents atypical signs.

red flags

Intense occipital pain with a sudden and progressive onset that is accompanied by meningeal signs (neck stiffness), fever, explosive vomiting or focal neurological deficit (extremity paresis, nystagmus), which rules out simple Arnold neuralgia and requires subarachnoid hemorrhage or meningitis to be ruled out.

Standard management

  • Local infiltration of the greater occipital nerve at Arnold's point with local anesthetic (1% or 2% lidocaine) combined with a corticosteroid (triamcinolone 20-40 mg), with both diagnostic and therapeutic value
  • Gabapentin — 300-900 mg/day
  • Pregabalin — 75-150 mg/day
  • Muscle relaxants such as Thiocolchicoside or Cyclobenzaprine in the acute phase if significant muscle contracture coexists.

Educational guidance for study. It is NOT a prescription recommendation. The actual choice depends on the cause, the patient, and current guidelines.

Area
Neurology
Listed causes
5
Treatment options
4
Download Epistemis