EpistemisAllosteric regulation
Biochemistry · Enzymes and kinetics
![Negative allosteric modulators (NAMs) move agonist dose-response curves to higher agonist concentrations by decreasing agonist affinity and/or decreasing maximal response by decreasing agonist efficacy. Plot shows receptor response (%) as a function of logarithmic agonist concentration ([Aug]). This is just an example and the units of concentration do not matter. Solid curve: original agonist respo](/assets/atlas/bioq-bq-0029.webp)
The guided interpretation is available in the app
Epistemis explains the visible findings, their rationale, and important mimics through guided interpretation and clinical pearls. Free and available offline.
Epistemis is educational review material. It is not a medical device, does not diagnose or prescribe treatment, and does not replace formal medical training, current clinical guidelines, or professional clinical judgment.
- Category
- Enzymes and kinetics
- Difficulty
- advanced
- Type
- Diagram
Origin: 5-HT2AR · CC0 · Wikimedia Commons · License CC0
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