EpistemisBerlin Definition of Acute Respiratory Distress Syndrome
Grades the distress by the PaO₂/FiO₂ ratio measured with at least 5 cmH₂O of positive pressure at the end of expiration. It includes correction for barometric pressure, essential in high-altitude cities where the uncorrected ratio overdiagnoses.
Required inputs
| Variable | Example value |
|---|---|
| Arterial PaO₂ (mmHg) | 80 |
| FiO₂ (fraction, 0.21 to 1.0) | 0.6 |
| PEEP or CPAP applied (cmH₂O) | 8 |
| Altitude above sea level (meters) | 0 |
| Onset in the week following a known insult or respiratory worsening (temporal criterion) | — |
| Bilateral opacities not explained by effusion, atelectasis or nodules | — |
| Edema not explained exclusively by heart failure or volume overload | — |
Run the calculation in the app
This page explains the score but does not run it. In Epistemis, the calculator validates units, flags values outside physiological ranges, and provides the interpretation that a number alone cannot convey.
Epistemis is educational review material. It is not a medical device, does not diagnose or prescribe treatment, and does not replace formal medical training, current clinical guidelines, or professional clinical judgment.
- Specialty
- Pneumology and Respiratory
- Area
- Internal Medicine
- Variables
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