Clinical Biochemistry: Metabolism of Xenobiotics - Reference Treatise and Physiopathological Correlation

Biochemistry · Basic Sciences

How it begins

Mecanismos enzimáticos de funcionalización y conjugación, sistemas de transporte transmembrana, regulación molecular y transcripcional a través de receptores nucleares, farmacogenética de poblaciones, toxicología clínica de la bioactivación e interacciones metabólicas complejas en el organismo humano.

What it covers

1. · Structural Classification of Xenobiotics
2. · The Cytochrome P450 (CYP) Superfamily
3. · The Stages of the Catalytic Cycle
4. · Conjugation Pathways and Endogenous Cofactors
5. · The ABC Family Efflux Machinery
6. · The Family of Ligand-Sensitive Nuclear Receptors
7. · Phenotypic Classification of Metabolizers
8. · Bioactivation and Electrophilic Stress
9. · Neonatal and Pediatric Metabolism
10. · Complex Diagnostic Clinical Vignettes
11. · Integrating Clinical and Neurosurgical Decision Matrix