Male Reproductive Endocrinology

Internal Medicine · Clinical Specialties

How it begins

Fisiología del eje hipotálamo–hipófisis–gonadal, espermatogénesis, acción androgénica, hipogonadismo, disfunción eréctil, fertilidad masculina, envejecimiento gonadal y neoplasias testiculares. Cobertura exhaustiva con correlaciones clínicas y guías de manejo actualizadas.

What it covers

1. The Hypothalamic-Pituitary-Gonadal Axis
2. · 1.1 Hypothalamus: GnRH and its regulation
3. · 1.2 Pituitary: LH, FSH and their gonadal receptors
4. · 1.3 Testicle: functional anatomy and compartmental organization
5. Androgens: Biosynthesis, Transport and Action
6. · 2.1 Testosterone biosynthesis: complete steroidogenesis
7. · 2.2 Circulating testosterone: fractions and their clinical relevance
8. · 2.3 Androgen Receptor (AR): molecular mechanism of action
9. · 2.4 Systemic physiological effects of testosterone
10. Spermatogenesis: from the Stem Cell to the Sperm
11. · 3.1 Phases of spermatogenesis
12. · 3.2 Regulation of testicular temperature
13. · 3.3 Spermogram: WHO 2021 parameters and their interpretation
14. Male Hypogonadism
15. · 4.1 Pathophysiological classification
16. · 4.2 Clinical manifestations according to life stage
17. · 4.3 Testosterone Replacement Therapy (TRT): principles and follow-up
18. Erectile Dysfunction
19. · 5.1 Physiology of erection: vasoactive mechanism
20. · 5.2 Etiological classification and differential diagnosis
21. Male Fertility and Infertility
22. · 6.1 Classification of azoospermia: the most important diagnosis
23. · 6.2 Treatable causes of male infertility
24. · 6.3 Assisted reproduction techniques (ART) and their indications
25. Male Gonadal Aging
26. · 7.1 Physiological changes in the HPG axis with aging
27. · 7.2 PADAM symptoms and diagnosis
28. Testicular Neoplasms
29. · 8.1 Classification and biology of germ cell tumors (GCT)
30. · 8.2 Impact of oncological treatment on gonadal function
31. Integrated Diagnostic Matrix