Antimicrobial Pharmacology

Antimicrobial Pharmacology — Expert Level

How it begins

Análisis exhaustivo de antibacterianos, antifúngicos, antivirales y antiparasitarios: mecanismos moleculares, farmacocinética-farmacodinamia, espectro, resistencia y correlaciones clínicas de máxima relevancia.

What it covers

1. General Principles of Antimicrobial PK/PD
2. · The Minimum Inhibitory Concentration (MIC) — The Central Parameter
3. · The Three PK/PD Patterns and Their Therapeutic Transcendence
4. · General Mechanisms of Antibacterial Action
5. · Bactericides vs. Bacteriostatics — Clinical Relevance
6. Betalactams — Bacterial Wall Inhibitors
7. · Penicillins — The First Antibiotic
8. · Cephalosporins — The Generation as a Guide to the Spectrum
9. · Carbapenems — The Last Resort Antibiotics for Gram–
10. Glycopeptides — Vancomycin and Derivatives
11. · Other Glycopeptides and Lipoglycopeptides
12. Aminoglycosides — Concentration-Dependent Bactericides
13. Macrolides, Clindamycin and Linezolid
14. · Macrolides
15. · Clindamycin (Lincosamide)
16. · Oxazolidinones — Linezolid and Tedizolid
17. Tetracyclines and Glycylcyclines
18. · Tigecycline — Broad Spectrum Glycylcycline
19. Fluoroquinolones — Broad Spectrum Antibacterials
20. Other Relevant Antibacterials
21. · Metronidazole — The Anaerobicide Par Excellence
22. · Cotrimoxazole (TMP-SMX) — Sequential Synergy in the Folate Pathway
23. · Polymyxins (Colistin and Polymyxin B) — The Last Resource in Gram–
24. · Daptomycin — The Bactericidal Lipopeptide
25. · Fosfomycin
26. Anti-tuberculosis and Antimycobacterial Drugs
27. · First Line Drugs — The HRZE Scheme
28. · New Drugs against MDR-TB and XDR-TB
29. Antifungals — Mechanisms and Clinic
30. · Polyenes — Amphotericin B
31. · Azoles — The Most Prescribed Antifungal Class
32. · Echinocandins — Fungal Wall Inhibitors
33. Antivirals — Viral Cycle Inhibitors
34. · Antiherpesvirals — Viral DNA Polymerase Inhibitors
35. · Antiretrovirals — HIV Treatment
36. · Direct Action Antivirals (DAA) for HCV
37. · Antivirals for Influenza and SARS-CoV-2
38. Antiparasitics — Protozoa and Helminths
39. · Antimalarials (Antimalarials)
40. · Anthelminths — Benzimidazoles and Others
41. Antimicrobial Resistance — The Global Crisis
42. · Resistance Mechanisms — Integrated Review
43. · WHO Priority Pathogens (Priority Pathogens, 2017 and 2024)
44. Rational Use and Antimicrobial Stewardship
45. · The PROA Principles: The "5Ds" of Stewardship
46. · Surgical Antibiotic Prophylaxis — Fundamental Principles
47. · De-escalation Strategies and Switch IV-Oral