Pharmacology of the Autonomous Nervous System

Pharmacology · Clinical Bases

How it begins

Análisis exhaustivo de los receptores, neurotransmisores y fármacos que modulan el sistema nervioso simpático y parasimpático, con mecanismos moleculares precisos, farmacocinética y correlaciones clínicas de alta relevancia terapéutica.

What it covers

1. Organization of the Autonomous Nervous System
2. · General Architecture: Pre and Postganglionic Neurons
3. · Functional Comparison: Friendly vs. Parasympathetic
4. Autonomic Neurotransmission
5. · Synthesis, Storage, Release and Termination of Acetylcholine
6. · Synthesis, Storage, Release and Termination of Norepinephrine
7. Adrenergic Receptors: Types, Distribution and Signaling
8. · Alpha Adrenergic Receptors (α₁ and α₂)
9. · Beta Adrenergic Receptors (β₁, β₂, β₃)
10. · Dopaminergic Receptors in the ANS
11. Sympathomimetics: α and β agonists
12. · Endogenous and Clinical Catecholamines
13. · Selective β₂ Agonists — Bronchodilators
14. · α₁ Agonists — Vasoconstrictors and Decongestants
15. · Indirect and Mixed Sympathomimetics
16. · Central α₂ Agonists — Central Action Antihypertensives
17. Sympatholytics: α and β antagonists
18. · α Blockers (Alpha Blockers)
19. · Beta blockers (β-blockers, BB)
20. Cholinergic Receptors: Muscarinic and Nicotinic
21. · Muscarinic Receptors (M₁–M₅)
22. · Nicotinic Receptors (nAChR)
23. Cholinomimetics: Direct Muscarinic Agonists
24. Anticholinergics: Muscarinic Blockers
25. · Belladonna Alkaloids
26. · Antimuscarinics for Specific Clinical Use
27. Ganglionic Blockers
28. Neuromuscular Junction Drugs
29. Acetylcholinesterase Inhibitors (Anti-AChE)
30. Synthesis, Metabolism and Therapeutic Targets of Catecholamines
31. · Drugs that Interfere with Catecholamine Synthesis
32. · Drugs That Interfere with the Storage and Release of Catecholamines
33. · MAOIs and Dangerous Drug Interactions
34. Integration: Clinical Applications of the ANS
35. · Pharmacology of Glaucoma
36. · Pharmacology of Arterial Hypertension — Role of the ANS
37. · Pharmacology of Acute Heart Failure — The Use of Inotropes
38. · Sympathomimetic Toxidrome vs. cholinergic