Pharmacology of the Digestive System

Pharmacology of the Digestive System — Expert Level Guide

How it begins

Análisis exhaustivo de los mecanismos de acción, clasificación, farmacocinética, correlaciones clínicas y uso racional de los agentes farmacológicos que modulan la función gastrointestinal, hepática y pancreática.

What it covers

1. Digestive System
2. 1. Introduction and Physiological Bases
3. · 1.1 The Enteric Nervous System (ENS)
4. · 1.2 Neuroendocrine Control of Acid Secretion
5. · 1.3 Gastrointestinal Hormones of Pharmacological Relevance
6. 2. Pharmacology of Acid Secretion
7. · 2.1 Proton Pump Inhibitors (PPIs)
8. · 2.2 H2 Receptor Antagonists (Anti-H2)
9. · 2.3 Antacids
10. · 2.4 Prostaglandin Analogs — Misoprostol
11. 3. Helicobacter pylori — Pharmacology of Eradication
12. · 3.1 Antimicrobial Agents with Anti-H. Activity. pylori
13. · 3.2 Bismuth in Eradication
14. · 3.3 Eradication Regimes
15. 4. Pharmacology of GERD
16. · 4.1 Principles of Treatment
17. · 4.2 Baclofen in Refractory GERD
18. · 4.3 Alginate in Postprandial GERD
19. · 4.4 GERD in Pregnancy
20. 5. Gastropathy due to NSAIDs and Pharmacological Strategies
21. · 5.1 Pathophysiology of Gastric Damage due to NSAIDs
22. · 5.2 Gastrointestinal Risk Stratification
23. · 5.3 Selective COX-2 Inhibitors (Coxibs)
24. 6. Drugs That Modify Gastrointestinal Motility
25. · 6.1 Prokinetics
26. · 6.2 Antispasmodics
27. · 6.3 Sucralfate
28. 7. Laxatives and Constipation Treatment
29. · 7.1 Classification by Mechanism
30. 8. Antidiarrheal
31. · 8.1 Antiperistaltics Opioids
32. · 8.2 Bismuth Subsalicylate
33. · 8.3 Antisecretory: Racecadotril (Acetorphan)
34. · 8.4 Oral Rehydration Salts (ORS)
35. · 8.5 Treatment of Diarrhea due to C. difficile
36. 9. Irritable Bowel Syndrome — Pharmacology
37. · 9.1 Pharmacological Treatment by Subtype
38. 10. Inflammatory Bowel Disease (IBD)
39. · 10.1 Aminosalicylates (5-ASA)
40. · 10.2 Corticosteroids
41. · 10.3 Classic Immunomodulators
42. · 10.4 Biological Agents
43. 11. Liver Pharmacology
44. · 11.1 Chronic Hepatitis due to HBV
45. · 11.2 Chronic Hepatitis due to HCV
46. · 11.3 Liver Cirrhosis and its Complications
47. · 11.4 Autoimmune Hepatitis
48. · 11.5 NASH/MASH (Metabolic Steatohepatitis)
49. 12. Pancreatic Pharmacology
50. · 12.1 Exocrine Pancreatic Insufficiency (EPI)
51. · 12.2 Acute Pancreatitis
52. · 12.3 Chronic Pancreatitis — Pain
53. 13. Antiemetics
54. · 13.1 5-HT3 Antagonists (Setrons)
55. · 13.2 NK1 Antagonists (Substance P Antagonists)
56. · 13.3 Corticosteroids
57. · 13.4 Olanzapine
58. · 13.5 Other Antiemetics
59. 14. Probiotics, Prebiotics and Fecal Microbiota Transplantation
60. · 14.1 Probiotics
61. · 14.2 Fecal Microbiota Transplantation (FMT)
62. 15. Pharmacology of Obesity and Metabolic Disorders
63. · 15.1 GLP-1 Agonists (GLP-1 RA)
64. · 15.2 Orlistat
65. · 15.3 Other Drugs for Obesity
66. · 15.4 SGLT2 Inhibitors — GI and Metabolic Implications