Adaptive Immunity — Medical Immunology

Immunology · Basic Sciences

How it begins

La inmunidad adaptativa (también denominada inmunidad adquirida o específica) constituye el segundo gran pilar del sistema inmunitario de los vertebrados con mandíbula. A diferencia de la inmunidad innata, que opera mediante patrones de reconocimiento estereotipados y de respuesta inmediata, el sistema adaptativo es capaz de generar receptores de unión antigénica de especificidad prácticamente ilimitada, montar…

What it covers

1. Adaptive Immunity
2. Introduction and Fundamental Properties
3. · Defining Properties of the Adaptive System
4. · Innate Immunity vs. Adaptive Immunity
5. · Main Cellular Components
6. T Lymphocyte Biology
7. · Ontogeny and Thymic Development
8. · T Cell Receptor (TCR) and CD3 Complex
9. · T Lymphocyte Activation: The Three Signals
10. · CD4+ Helper T Lymphocyte Subpopulations
11. · Cytotoxic CD8+ T Lymphocytes (CTL)
12. · Regulatory T lymphocytes (Treg)
13. Major Histocompatibility and Antigenic Presentation Complex
14. · Antigenic Processing and Presentation Routes
15. · Professional Antigen Presenting Cells
16. B Lymphocyte Biology and Humoral Response
17. · Development of the B Lymphocyte in the Bone Marrow
18. · B Lymphocyte Activation and Germinal Center Reactions
19. Antibodies: Structure, Isotypes and Effector Functions
20. · Human Immunoglobulin Isotypes
21. · Effective Mechanisms of Antibodies
22. Immunological Memory
23. · Respuesta Primaria vs. Secundaria
24. Immunological Tolerance
25. · Central Tolerance
26. · Peripheral Tolerance
27. Advanced Clinical Correlations
28. · Primary Immunodeficiencies Related to the Adaptive System
29. · Autoimmunity: Molecular Mechanisms
30. · Hypersensitivity: Gell and Coombs Classification
31. · Transplant Rejection
32. · Cancer Immunotherapy
33. · Immunological Principles of Vaccination
34. Integration of Effector Mechanisms: Adaptive and Innate
35. · The Complement as an Effector of the Humoral Response
36. · Adaptive-Innate Interaction: Amplification Circuits
37. · Immunosenescence: The Aging of the Adaptive System