Immunology, Immunopathology and Forensic Pathology

General Pathology · Basic Sciences

How it begins

Hematopoyesis, inmunidad innata y adaptativa, macrófagos, linfocitos T y B, tolerancia inmunológica, hipersensibilidad (Tipos I–IV), autoinmunidad, inmunodeficiencias y nociones de medicina legal y patología forense. Basado en las diapositivas de clase.

What it covers

1. Hematopoiesis and Bone Marrow
2. · Hierarchy of Hematopoiesis
3. Innate Immunity
4. · Components of Innate Immunity
5. Steps of Inflammation: The 5 R's
6. · The 5 Stages of the Inflammatory Response
7. The Importance of the Macrophage
8. · Origin and Pharmacokinetics of the Macrophage
9. · Macrophage Activation: M1 vs. M2
10. Adaptive Immunity
11. · CD4+ T lymphocytes: The Orchestra Directors
12. · CD8+ T Lymphocytes (CTL): The Specific Killers
13. · B Lymphocytes and Antibodies: Humoral Immunity
14. Immunological Tolerance
15. · Central Tolerance
16. · Peripheral Tolerance
17. Immunopathology
18. Type I Hypersensitivity: Immediate / Allergy
19. · Complete Pathophysiological Mechanism
20. · Clinical Manifestations: from discomfort to death
21. · Atopy Risk Factors: genetic and environmental predisposition
22. Type II Hypersensitivity: Antibodies against Cells or Tissues
23. · Damage Mechanisms in Type II
24. Type III Hypersensitivity: Immune Complexes
25. · Mechanism of Damage by Immune Complexes
26. Type IV Hypersensitivity: Mediated by T Cells
27. · General Mechanism
28. Autoimmunity
29. · Genetic Factors: The Role of HLA and Other Genes
30. · Systemic Lupus Erythematosus (SLE): Complex Autoimmunity Model
31. · Systemic Sclerosis (Scleroderma)
32. Immunodeficiencies
33. · Secondary Immunodeficiencies (Acquired)
34. · Most Important Primary Immunodeficiencies
35. Forensic Pathology and Legal Medicine
36. · Fundamental Definitions
37. · Classification of Manner of Death
38. · Cause, Mechanism and Mode of Death
39. Master Table: Gell and Coombs Classification