Intensive Medicine: Severe Trauma, Burns and Toxicology in the ICU

Intensive Medicine · Clinical Specialties

How it begins

Un compendio exhaustivo y riguroso sobre el abordaje fisiopatológico multiorgánico en pacientes con trauma de alta energía, choque distributivo por quemaduras mayores e intoxicaciones graves que comprometen la vida. Integra bases moleculares, guías internacionales y protocolos de soporte vital avanzado en la Unidad de Cuidados Intensivos.

What it covers

1. Pathophysiology of Trauma: From the "Triangle of Death" to the Lethal Diamond
2. · Trauma-Induced Coagulopathy (TIC): Molecular Mechanisms
3. Damage Control Resuscitation (DCR) and Mass Transfusion Protocols
4. · Fundamental Principles of DCR
5. Severe Traumatic Brain Injury (TBI) and Intracranial Hypertension
6. · Pathophysiology of Cerebral Edema: Cytotoxic vs. Vasogenic
7. Severe Chest Trauma: Unstable Chest and Pulmonary Contusion
8. · Pathophysiology of the Unstable Chest (Flail Chest)
9. Abdominal and Pelvic Trauma: Abdominal Compartment Syndrome
10. · Intra-abdominal Hypertension (IAH) vs. Abdominal Compartment Syndrome (ACS)
11. High Energy Musculoskeletal Trauma: Crush Syndrome and Rhabdomyolysis
12. · Cellular Pathophysiology of Rhabdomyolysis
13. Pathophysiology of the Great Burn: The Hypermetabolic-Inflammatory Syndrome
14. · Cuthbertson's Hemodynamic Phases: Ebb vs. flow
15. Water Resuscitation in the Great Burn: Formulas and Avoidance of Overload
16. · The Classic Resuscitation Formulas
17. Inhalation Injury and Gas Toxicity: CO and Cyanide
18. · Pathophysiology of Airway Damage: Thermal vs. Chemist
19. Emergency Surgical Management in Large Burns: Escharotomies and Fasciotomies
20. · Pathophysiology of Circumferential Eschar Ischemia
21. Nutrition, Metabolic Support and Pharmacological Modulation of Hypermetabolism
22. · Calculation of Nutritional Requirements: Indirect Calorimetry vs. Formulas
23. Sepsis and Infectious Complications in the Burn Patient
24. · Why standard SIRS and qSOFA criteria fail
25. General Principles of the Intoxicated Patient: Toxidromas and Decontamination
26. · Clinical Recognition of the Main Toxidromes
27. Toxicity due to Organophosphate and Carbamate Intoxication
28. · Pathophysiology of Acetylcholinesterase (AChE) Blockade
29. Poisoning by Cardiovascular Drugs: Beta Blockers and Calcium Antagonists
30. · Pathophysiology of Shock due to L-type Channel Blockage
31. Paracetamol (Acetaminophen) Poisoning and Acute Liver Failure
32. · The Metabolic Pathway of Liver Cell Damage
33. Toxicity due to Toxic Alcohols and Glycols: Methanol and Ethylene Glycol
34. · Pathophysiology of Lethal Metabolism
35. Overdose of Opioids, Sedatives and Tricyclic Antidepressants
36. · Intoxication by Tricyclic Antidepressants (TCA): The Cardiovascular Risk
37. Extracorporeal Purification Techniques in Toxicology: EXTRIP Consensus
38. · The Physicochemical Properties of the Dialyzable Xenobiotic
39. Emergency Pharmacology in Toxicology: Guide to Specific Antidotes
40. · Table of Critical Antidotes of Immediate Availability