Neurosciences: Plasticity, Development and Aging

Neurosciences · Basic Sciences

How it begins

Desde la neurulación embrionaria hasta la neurodegeneración senil: mecanismos moleculares, períodos críticos, reorganización cortical y las bases biológicas del declive cognitivo.

What it covers

1. Introduction: The Brain as a System in Perpetual Change
2. Neural Development: From Neurulation to Synapse
3. · 1.1. Neuronal Migration: Molecular Mechanisms
4. · 1.2. Neuronal Differentiation, Identity Specification and Apoptosis
5. · 1.3. Synaptogenesis: Construction of Circuits
6. · 1.4. Myelination: The Longest Maturation Process
7. Critical Periods of Development
8. · 2.1. The Visual Critical Period: Ocular Dominance
9. · 2.2. Critical Periods for Language and Other Functions
10. · 2.3. Common Mechanisms of Critical Periods
11. Neuroplasticity: Types, Levels and Mechanisms
12. · 3.1. LTP and LTD: The Synaptic Basis of Plasticity
13. · 3.2. Homeostatic Plasticity: Maintaining Balance
14. · 3.3. Structural Plasticity: Beyond the Synapse
15. Adult Neurogenesis
16. · 4.1. Neurogenesis in the Hippocampus (Subgranular Zone, SGZ)
17. · 4.2. Subventricular Zone (SVZ) and Olfactory Bulb
18. · 4.3. Adult Neurogenesis: Current Debate and Therapeutic Perspectives
19. Plasticity of Cortical Maps and Rehabilitation
20. · 5.1. Reorganization by Experience
21. · 5.2. Post-Injury Reorganization: Basis of Rehabilitation
22. Brain Aging: Normal Changes
23. · 6.1. Morphological Changes of Normal Aging
24. · 6.2. Molecular and Cellular Changes of Aging
25. · 6.3. Normal Cognitive Changes of Aging
26. Cognitive and Brain Reserve
27. Dementia and Neuropathology of Aging
28. · 8.1. Alzheimer's Disease: Pathogenesis in Depth
29. · 8.2. Other Neurodegenerative Dementias
30. · 8.3. Mild Cognitive Impairment (MCI) and Biomarkers
31. Neuroprotection, Reserve and Therapeutic Strategies
32. Clinical Synthesis: Plasticity, Development and Aging