Clinical Nutrition: Fundamentals of Nutrition and Metabolism — Expert Level Academic Guide

Clinical Nutrition · Clinical Specialties

How it begins

Un análisis exhaustivo de los mecanismos moleculares, las rutas de transducción de señales, la bioquímica metabólica avanzada y la toma de decisiones clínicas aplicadas a la terapia nutricional en el paciente crítico y crónico.

What it covers

1. Physiology and Metabolism
2. Physiology of Macronutrient Digestion and Absorption
3. · Enzymatic Digestion and Hydrolysis of Carbohydrates
4. · Apical and Basolateral Transport Mechanisms
5. · Lipid Digestion and Absorption
6. Cellular Bioenergetics and Hormonal Regulation
7. · Mitochondrial Thermodynamics: The Electron Transport Chain (ETC)
8. · Cellular Energy Sensors: AMPK and mTOR
9. Carbohydrate Metabolism and Related Pathology
10. · Points of Allosteric and Hormonal Regulation of Glycolysis
11. · Gluconeogenesis and the Cori Cycle
12. Lipids, Lipoproteins and Pathophysiology of Dyslipidemia
13. · Lipid Transport Routes
14. · Biochemistry of Atheroma Plaque Formation
15. Protein Metabolism and Urea Cycle
16. · Amino Acid Catabolism and Transamination
17. · The Urea Cycle (Krebs-Henseleit Cycle)
18. Water-soluble Micronutrients
19. Fat-soluble Micronutrients
20. · Calcium Homeostasis and Hormonal Mechanism of Vitamin D
21. · Vitamin K Cycle and Carboxylation Dependent Coagulation Factors
22. Trace Elements and Essential Minerals
23. · Iron Metabolism and Cellular Homeostasis
24. Regulation of Intake, Energy Expenditure and Balance
25. · Hypothalamic Axis of Intake Regulation
26. · Components of Total Energy Expenditure (GET)
27. · Measurement of Energy Expenditure: Indirect Calorimetry
28. Pathophysiology of Hospital Malnutrition
29. · Physiology of Metabolic Adaptation to Simple Fasting (Uncomplicated Starvation)
30. · Physiopathological Differences: Marasmus versus Kwashiorkor
31. Refeeding Syndrome
32. · Pathophysiology of Electrolyte Collapse
33. · Clinical Manifestations of Established Refeeding Syndrome
34. Enteral Nutritional Support
35. · Physiological Advantages of Enteral Nutrition over Parenteral Nutrition
36. · Selection of Enteral Access Routes
37. · Types of Enteral Nutrition Formulas
38. Parenteral Nutritional Support (PN)
39. · Absolute Indications for Parenteral Nutrition
40. · The Critical Osmolarity Barrier: Peripheral NP versus Central NP
41. · Evolution of Parenteral Lipid Emulsions
42. Immunonutrition and Metabolic Responses in the Critically Ill Patient
43. · Phases of the Metabolic Stress Response: The Cuthbertson Model
44. · Biological Foundations of Immunonutrients