Epistemis

Neurocognitive Disorders and Dementia

Neurocognitive Disorders and Dementia — Expert Level Reference

How it begins

Del dominio cognitivo a la decisión clínica: definiciones DSM-5, evaluación neuropsicológica y biomarcadores, las grandes enfermedades neurodegenerativas y vasculares, las demencias rápidamente progresivas y reversibles, el delirium, los síntomas conductuales, el tratamiento y el cuidado, con correlación clínica de nivel experto.

What it covers

  1. Concepts, terminology and classification
  2. · The continuum: normal cognition — MCI — dementia
  3. · Dementia classification axes
  4. · Epidemiology
  5. Cognitive domains and neuropsychological evaluation
  6. · The six cognitive domains
  7. · Cognitive screening instruments
  8. · The interview with the informant and the functional evaluation
  9. Diagnostic approach, neuroimaging and biomarkers
  10. · Basic analytical study
  11. · Structural neuroimaging
  12. · Functional and molecular neuroimaging
  13. · Biomarkers and the ATN framework
  14. Alzheimer's disease
  15. · Pathophysiology: the amyloid cascade and tau pathology
  16. · Clinical manifestations
  17. · Diagnosis and treatment
  18. Vascular dementia and vascular cognitive impairment
  19. · Mechanisms and subtypes
  20. · Differentiating clinical features
  21. Lewy body dementia and Parkinson's disease dementia
  22. · Nuclear clinical characteristics of DLB
  23. Frontotemporal lobar degeneration
  24. · Clinical variants
  25. · Overlap with motor neuron disease
  26. Rapidly progressive dementias
  27. · Prion disease (Creutzfeldt-Jakob)
  28. · Autoimmune encephalitis and autoimmune dementia
  29. · Other causes of rapid progression
  30. Secondary and potentially reversible dementias
  31. · Reversible causes according to mechanism
  32. · Normotensive hydrocephalus
  33. Delirium and its differentiation from dementia
  34. · Nuclear characteristics
  35. · Delirium versus dementia
  36. Psychological and behavioral symptoms of dementia (SPCD)
  37. · Spectrum of symptoms
  38. Pharmacological treatment
  39. · Acetylcholinesterase inhibitors
  40. · Memantine
  41. · Disease-modifying therapies (anti-amyloid)
  42. Non-pharmacological management, caregiver and ethical-legal aspects
  43. · Non-pharmacological interventions
  44. · The caregiver: a therapeutic target
  45. · Ethical-legal aspects
  46. Prevention and modifiable risk factors
  47. · Modifiable risk factors throughout life
  48. Diagnostic integration and synthesis
  49. · Differential master table of major dementias

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Neurology
Category
Clinical Specialties
Type
Study Guide
Sections
49
Reviewed
2026-08-02
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