Epistemis

Ejaculatory pain

Specialty: Nephrology and urology.

  • odynorgasmia
  • painful ejaculation
  • painful male dysorgasmia

Why it occurs

  • Chronic bacterial or non-bacterial prostatitis (muscle contraction during climax generates pressure on an inflamed prostate)
  • Seminal vesiculitis (infection or inflammation of the seminal vesicles that alters the composition and emission of semen)
  • Obstruction of the ejaculatory ducts (due to Müllerian duct cysts, calcifications or duct stones that prevent the free passage of semen, causing painful spasm)
  • Adverse effect of psychotropic drugs (selective serotonin reuptake inhibitors such as paroxetine, or antipsychotics that alter sympathetic ductal motility)
  • Urethral or bladder neck stenosis (the forced passage of ejaculate through a narrow duct generates acute burning pain)

Initial workup

Spermoculture to rule out bacterial infections or other STDs in the semen; high-resolution transrectal ultrasound to assess the status of the seminal vesicles, prostate and rule out obstructive cysts; urine culture obtained after an orgasm; Pelvic MRI if there is suspicion of complex obstructive malformation.

red flags

Persistent ejaculatory pain associated with refractory hematospermia (blood in semen), palpable hard nodules in the prostate in people over 50 years of age (suspected prostate cancer), or associated unexplained fever.

Standard management

  • Levofloxacin — 500 mg daily orally for 21 to 28 days if an infectious bacterial cause of the prostatic or seminal vesicles is confirmed
  • Ibuprofen — 400 mg every 8 hours orally for 10 days to reduce inflammation and ductal edema
  • Tamsulosin (0.4 mg daily orally to relax the smooth fibers of the ejaculatory ducts and prostate, reducing ejaculatory spasm).

Educational guidance for study. It is NOT a prescription recommendation. The actual choice depends on the cause, the patient, and current guidelines.

Area
Nephrology and urology
Listed causes
5
Treatment options
3
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