Epistemis

Persistent hiccups

Specialty: Gastrointestinal.

  • hiccup
  • singult

Why it occurs

  • Gastric distension/reflux
  • Diaphragmatic irritation
  • CNS alteration
  • Metabolic (uremia)
  • Drugs

Initial workup

Review drugs and gastroesophageal causes; If it lasts >48 hours, look for a thoracic/CNS cause.

red flags

Intractable hiccups >48 h → look for organic cause (CNS, mediastinum, metabolic).

Standard management

  • Physical maneuvers — first measure
  • Metoclopramide / baclofen / gabapentin — persistent hiccups

Educational guidance for study. It is NOT a prescription recommendation. The actual choice depends on the cause, the patient, and current guidelines.

Area
Gastrointestinal
Listed causes
5
Treatment options
2
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