Sense of suffocation when swallowing
Specialty: Respiratory.
Why it occurs
- Cricopharyngeal dysfunction or achalasia of the upper esophageal sphincter (failure to relax the sphincter that causes stagnation of the bolus in the hypopharynx and subsequent overflow into the airway)
- Myasthenia gravis or amyotrophic lateral sclerosis (weakness of the pharyngeal and laryngeal muscles with ineffective glottic closure during swallowing)
- Sequelae of brainstem cerebrovascular accident (CVA) (pseudobulbar palsy with abolition of the protective airway reflex)
- Large Zenker's diverticulum (accumulation of food in the diverticular pouch that is passively regurgitated and aspirated when adopting certain postures)
- Unilateral vocal cord paralysis (incomplete glottic closure that allows fluids to pass into the trachea).
Initial workup
Videofluoroscopy of swallowing or modified barium swallow (gold standard to evaluate the swallowing mechanism and document silent or overt aspiration); Nasofibrolaryngoscopy with sensory evaluation of swallowing (FEES); Upper digestive endoscopy; High resolution esophageal manometry.
red flags
Violent and immediate cough after ingesting liquids or solids associated with perioral cyanosis, localized wheezing of new appearance (suggestive of aspiration of a foreign body), pneumonia due to repeated aspiration, or rapid weight loss due to dysphobia (fear of eating due to the risk of suffocation).
Standard management
- Management is fundamentally rehabilitative through safe swallowing techniques and adaptation of the consistency of foods with thickeners.
- Pyridostigmine — acetylcholinesterase inhibitor, 60 mg orally every 6 hours for confirmed myasthenia gravis
- Botulinum toxin (localized injection in the cricopharyngeal muscle performed by a specialist in selected cases of sphincter dysfunction).
Educational guidance for study. It is NOT a prescription recommendation. The actual choice depends on the cause, the patient, and current guidelines.
- Area
- Respiratory
- Listed causes
- 5
- Treatment options
- 3