Biochemistry: Introduction and General Principles

Biochemistry · Basic Sciences

How it begins

Fundamentos de la química de la vida: composición molecular, propiedades del agua, equilibrios ácido-base, interacciones no covalentes, termodinámica biológica, bioenergética del ATP y organización metabólica celular

What it covers

1. Introduction to Biochemistry
2. · 0.1 History of Biochemistry
3. · 0.2 Biochemistry in the Context of Biomedical Sciences
4. Chemical Composition of Living Beings
5. · 1.1 Bioelements
6. · 1.2 The Four Large Classes of Biomolecules
7. · 1.3 Hierarchy of Molecular Organization
8. Water as a Universal Biological Solvent
9. · 2.1 Molecular Structure of Water
10. · 2.2 Biologically Relevant Physicochemical Properties
11. · 2.3 Solvation and Hydrophobicity
12. Acids, Bases and Biological Acid-Base Balance
13. · 3.1 Definitions and Fundamental Concepts
14. · 3.2 Henderson-Hasselbalch equation
15. · 3.3 Physiological Buffer Systems
16. · 3.4 Acid-Base Balance Disorders
17. Non-Covalent Interactions in Biomolecules
18. · 4.1 Cooperativity and Specificity
19. Biological Thermodynamics
20. · 5.1 First Principle of Thermodynamics
21. · 5.2 Second Principle and Entropy
22. · 5.3 Gibbs Free Energy (G)
23. · 5.4 Biochemical Standard Conditions and ΔG°'
24. · 5.5 Coupled Reactions — The Fundamental Principle of Bioenergetics
25. ATP and Cellular Bioenergetics
26. · 6.1 Chemical Structure of ATP
27. · 6.2 Group Transfer Potential and Energy Scale
28. · 6.3 Other Energy Carriers
29. Introduction to Metabolism
30. · 7.1 Stages of Catabolism
31. · 7.2 Characteristics of Metabolic Pathways
32. · 7.3 Integrated Hormonal Regulation: Metabolic States
33. Cell Compartmentation and Biochemistry of Organelles
34. Integrative Clinical Correlations
35. · 9.1 Inborn Errors of Metabolism — Garrodian Concept
36. · 9.2 Cancer Biochemistry — Warburg Effect
37. · 9.3 Summary Table — Fundamental Biochemical Principles
38. · Unifying Principle