Carbohydrate Metabolism — Medical Biochemistry

Biochemistry · Basic Sciences

How it begins

Análisis exhaustivo de las vías del metabolismo glucídico: glucólisis, ciclo de Krebs, gluconeogénesis, glucógeno, pentosas fosfato, fructosa, galactosa y su regulación hormonal integrada, con correlaciones clínicas de primer nivel.

What it covers

1. Overview of Glycid Metabolism
2. Digestion and Absorption of Carbohydrates
3. · Digestive Enzymes
4. · Monosaccharide Transporters
5. Glycolysis
6. · The Ten Reactions — Two Phases
7. · Regulation of Glycolysis
8. · Anaerobic Glycolysis and the Lactate Cycle
9. Pyruvate Dehydrogenase Complex (PDH)
10. · Structure, Subunits and Cofactors
11. Tricarboxylic Acid Cycle (Krebs Cycle / TCA)
12. · The Eight Reactions of the TCA Cycle
13. · Regulation of the TCA Cycle
14. · Anaplerotic Reactions — Cycle Maintenance
15. · TCA Mutations as Metabolic Oncogenes
16. Oxidative Phosphorylation and Total Energy Efficiency
17. · ATP Yield per Glucose Molecule
18. Gluconeogenesis (GNG)
19. · Gluconeogenic Substrates
20. · The Four Unique Enzymes of GNG
21. · Inter-organ Metabolic Cycles
22. Glycogen Metabolism
23. · Glycogen Synthesis (Glycogenogenesis)
24. · Glycogen Degradation (Glycogenolysis)
25. · Regulation of Glycogen Metabolism
26. · Glycogenosis (Glycogen Storage Diseases) — Complete Table
27. Pentose Phosphate Pathway (Phosphogluconate Pathway)
28. · Oxidative Phase — Irreversible
29. · Non-Oxidative Phase — Reversible
30. Fructose Metabolism
31. Galactose Metabolism
32. Integrated Hormonal Regulation of Glycid Metabolism
33. · Insulin: The Hormone of the Anabolic State
34. · Glucagon and AMPK: Regulators of Catabolism
35. · Integrated Metabolic States
36. Diabetes Mellitus — Biochemical Pathophysiology
37. · Diabetes Mellitus Type 1 — Absolute Insulin Deficiency
38. · Diabetes Mellitus Type 2 — Insulin Resistance and β-Cell Failure
39. · Biochemical Pathways of Chronic Diabetic Complications
40. · Pharmacology of Glycemic Control — Biochemical Mechanisms
41. Integration and Key Points of Carbohydrate Metabolism
42. · Metabolic Interconnections Map
43. · Master Regulatory Enzymes — Summary
44. · Key Inborn Errors — Quick Reference Table
45. · High Performance Points for Clinical Examination