Pain Medicine: Acute and Postoperative Pain — Anesthetic and Algological Specialty Treaty

Pain Medicine · Clinical Specialties

How it begins

Un tratado exhaustivo y detallado sobre la neurobiología de la nocicepción, la modulación central, el desarrollo de sensibilización espinal y el diseño de estrategias de analgesia multimodal de precisión encaminadas a evitar la transición hacia la cronicidad.

What it covers

1. Introduction and Ethics of Pain Relief: The Human and Physiological Dimension of Postoperative Pain
2. Peripheral Receivers and Signal Transduction: Primary Alarm Mechanisms
3. · Cellular mechanics of dermoepidermal transduction
4. A-delta and C fibers: Speed, Structure and Distribution of Afferent Pathways
5. · Biophysical differences in peripheral transmission
6. Synaptic Transmission in the Dorsal Horn: The First Relay and Spinal Modulation
7. · Microanatomy of the posterior horn and chemical neurotransmission
8. Ascending Pathways and Pain Matrix: The Journey of Sensory Information to the Brain
9. · Medullary tracts and supraspinal integration
10. Downward Modulation: The Endogenous Brake of the Nociceptive Signal
11. · Inhibitory and facilitatory pathways of central control
12. Peripheral Sensitization: Physiology of Inflammatory Soup
13. · The microenvironment of the surgical wound
14. Central Sensitization and Hyperalgesia: The Spinal Amplification Process
15. · The Wind-Up phenomenon and synaptic plasticity
16. Glia and Spinal Neuroinflammation: The Silent Role of Central Immunity
17. · Microglial and astrocyte activation
18. Transition from Acute to Chronic Pain: Physiology of Postoperative Chronification
19. · From physiological nociception to neuropathy induced by surgery
20. Systemic Pathophysiology and Clinical Responses to Acute Uncontrolled Pain
21. · The multi-organ impact of nociceptive aggression
22. Pain Metrology and Clinical Scales: The Search for Objective Measurement
23. · Multidimensional evaluation of the painful phenomenon
24. Psychosocial and Predictive Factors: The Cognitive Filter of Surgical Stimulus
25. · The impact of the psyche on spinal processing
26. Pharmacogenomics and Special Populations: The Personalization of Analgesic Management
27. · Genetic polymorphisms of Cytochrome P450
28. · Management of vulnerable populations
29. Intraoperative Nociception Monitoring: Objectifying the Response to Pain Under General Anesthesia
30. · Beyond conventional hemodynamic control
31. NSAIDs, Coxibs and Anti-inflammatories: Modulating the Origin of the Inflammatory Soup
32. · Mechanism of biochemical action and isoform selectivity
33. Paracetamol and Metamizole: Centrally Acting Non-Opioid Analgesics
34. · Paracetamol (Acetaminophen): Precision central mechanism of action
35. · Metamizole (Dipyrone): The highly effective spasmolytic analgesic
36. Systemic Opioids: Receptive Pharmacodynamics and Precision Clinical Profiles
37. · Molecular interaction and second messenger cascade
38. · Pharmacological Profiles of Commonly Used Opioids
39. Acute Opioid Tolerance and Hyperalgesia: The Paradoxes of Prolonged Opioid Therapy
40. · Two clinical entities with dissimilar molecular bases
41. Adjuvants in Acute Pain: Non-Opioid Synaptic Modulators
42. · Synaptic and neurochemical stabilization mechanisms
43. Local Anesthetics and Conduction Block: The Disruption of the Transmission Line
44. · Chemical structure and interaction with the Sodium channel
45. Neuroaxial Analgesia: Epidural and Intrathecal Control of Visceral Stimulus
46. · Modulation at the level of the spinal cord
47. Chest and Abdominal Wall Blocks: Ultrasound Applied to Wall Analgesia
48. · Ultrasound anatomy and fascial safety planes
49. Limb Blocks and Neuromonitoring: Selective Surgical Analgesia
50. · Plexus and peripheral nerve blocks under dual guidance
51. Patient Controlled Analgesia (PCA): Programming and Critical Safety Parameters
52. · The empowerment of the patient in the control of their analgesia
53. Preventive Analgesia and ERAS Protocols: Systemic Multimodal Planning
54. · The concept of preemptive analgesia (*Preemptive Analgesia*)
55. Pain in Major Abdominal and Thoracic Surgery: The Challenge of Acute Management
56. · Specific multimodal approaches of high complexity
57. Patients with Previous Tolerance and Addictions: The Scenario of High Algological Complexity
58. · Management of patients with chronic pain on chronic treatment with Opioids
59. Systemic Toxicity from Local Anesthetics: Emergency Diagnosis and Lipid Rescue
60. · Pathophysiology of systemic cellular collapse
61. Acute Pain Units (AUD): Organizational Structure and Quality Control of Care
62. · The clinical impact of specialized equipment