Emergencies: Specific Serious and High Complexity Infections

Emergency Room · Clinical Specialties

How it begins

La definición consensual de la Sepsis (Sepsis-3) la conceptualiza como una disfunción orgánica potencialmente mortal causada por una respuesta anómala o desregulada del huésped a una infección. El shock séptico representa un subgrupo de la sepsis en el que las alteraciones circulatorias, celulares y metabólicas son lo suficientemente profundas como para aumentar de manera significativa la mortalidad (superando el…

What it covers

1. The Cellular and Humoral Cascade: PAMPs, DAMPs and PRRs
2. Endothelial Dysfunction and Microcirculation Alteration
3. Tissue Hypoxia and Mitochondrial Dysfunction (Cytopathic Hypoxia)
4. Clinical Stratification Criteria: SOFA Score
5. Pathophysiology of Brain Damage and Blood-Brain Barrier (BBB)
6. Differential Diagnosis of CSF in the Emergency Room
7. Empirical Therapeutic Approach
8. · Adult from 18 to 49 years old:
9. · Adult ≥50 years old, Alcoholic or Immunocompromized:
10. Acute Viral Encephalitis (Herpes Simplex Type 1)
11. Pathophysiology of Abdominal Sepsis
12. Clinical Classification of Peritonitis
13. Severe Acute Cholangitis (Biliary Sepsis)
14. · Tokyo Stratification (TG18/TG13):
15. Physiopathological Mechanism of Fascial and Systemic Damage
16. Microbiological Classification
17. Suspicion Criteria: LRINEC Scale
18. ATS/IDSA Severity Criteria
19. · Major Criteria (at least one of them):
20. · Minor Criteria (at least three of them):
21. Specific Microbiology in Severe CAP
22. Therapeutic Approach and Support of Septic ARDS
23. · Ventilatory Management of Septic ARDS:
24. Pathophysiology of Endocardial Damage and Embolic Phenomena
25. Modified Duke Stratification: Key Criteria
26. · Major Criteria:
27. · Minor Criteria:
28. Empirical Therapeutic Approach
29. · Native Valve (Acute, Severe Sepsis):
30. · Prosthetic Valve (Installation 1 year after surgery):
31. Pathophysiology of Systemic Invasion of the Urinary Tract
32. Serious Complications: Emphysematous Pyelonephritis
33. · Classification by Wan et al. (Prognostic Stratification using CT):
34. Approach to Obstructive Urosepsis
35. Antimicrobial Treatment Targeted at Multiresistance
36. · Standard Empirical Scheme (Without ESBL Risk Factors):
37. Clinical Operational Definitions
38. Etiology and Risk of Bacterial Translocation
39. Risk Stratification Criteria: MASCC Scale
40. Empirical Therapeutic Schemes in Emergencies
41. · Monotherapy of Choice in High Risk Patients:
42. · Indications for Addition of Vancomycin (Coverage of Gram positives in emergencies):
43. PK/PD Parameters of Antimicrobial Families
44. Physiopathological Alterations of the Septic Patient
45. · 1. Increase in Distribution Volume (Vd)
46. · 2. Augmented Renal Clearance (ARC)
47. Sepsis and Septic Shock Management Protocol in Emergencies
48. · Immediate Phase (First Hour):
49. · Evaluation of Response to Resuscitation (Dynamic Phase):
50. Final Clinical Conclusions