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Major Neurological Syndromes

Major Neurological Syndromes — Expert Level Reference

How it begins

Los patrones sindrómicos cardinales con que la enfermedad neurológica se presenta ante el internista: conciencia, HTIC, meningitis, ictus, crisis, delirium, encefalopatías, síndromes motores, sensitivos, medulares, neuromusculares, de pares craneales, vestibulares, corticales, demencia y cefalea — con pruebas complementarias e integración diagnóstica.

What it covers

  1. The concept of major neurological syndrome
  2. · The temporal profile as the axis of reasoning
  3. Altered consciousness and coma syndrome
  4. · Clinical gradation of level of consciousness
  5. · Glasgow Coma Scale (GCS)
  6. · Examination of the comatose patient: signs of location of the trunk
  7. · Structural comma vs. toxic-metabolic
  8. · Systematic approach to coma of unknown cause
  9. · FOUR scale and limitations of the GCS
  10. · Prognosis of coma and brain death
  11. Intracranial hypertension syndrome
  12. · Clinical manifestations
  13. · Brain herniation syndromes
  14. · Management of HTIC and correlation with etiologies
  15. Meningeal syndrome
  16. · Exploration: signs of meningeal irritation
  17. · CSF analysis: the diagnostic key
  18. · Etiological correlation and management
  19. · Encephalitis: when the parenchyma becomes inflamed
  20. · Subarachnoid hemorrhage as meningeal syndrome
  21. Cerebrovascular syndrome (stroke)
  22. · Pathophysiology: ischemic penumbra
  23. · Etiological classification of ischemic stroke (TOAST)
  24. · Vascular topographic syndromes
  25. · Hemorrhagic stroke
  26. · Acute management and therapeutic correlation
  27. · Classic brainstem syndromes (alternating syndromes)
  28. · NIHSS scale and quantification of the deficit
  29. · Oxford Clinical Classification (Bamford / OCSP)
  30. Convulsive syndrome and status epilepticus
  31. · Classification of crises (ILAE)
  32. · Differential diagnosis: the great trap of syncope
  33. · Acute symptomatic crises: the internist approach
  34. · The postcritical period and Todd's paralysis
  35. · Study of the first crisis and considerations of chronic management
  36. Acute confusional syndrome (delirium)
  37. · Clinical subtypes
  38. · Delirium vs. dementia: the critical distinction
  39. · Etiology: the predisposing-precipitating model
  40. · Management
  41. Encephalopathic and dysautonomic syndromes
  42. · Major metabolic and toxic encephalopathies
  43. · Dysautonomic syndromes
  44. Pyramidal syndrome: upper motor neuron vs. lower
  45. · Amyotrophic lateral sclerosis: the paradigmatic mixed syndrome
  46. · Addressing weakness: locating the level
  47. Extrapyramidal and cerebellar syndromes
  48. · Extrapyramidal syndromes
  49. · Cerebellar syndrome
  50. Spinal cord syndrome
  51. · Topographic spinal syndromes
  52. Neuromuscular syndrome (PNS, junction and muscle)
  53. · Polyneuropathy and Guillain-Barré syndrome
  54. · Neuromuscular junction disorders
  55. · Myopathies
  56. Sensitive syndromes
  57. · Topographic patterns of sensory deficit
  58. · Semiology of neuropathic pain
  59. Cranial nerve and brainstem syndromes
  60. · Oculomotor and gaze syndromes
  61. · Facial paralysis: central vs. peripheral
  62. · Low torques and skull base syndromes
  63. Vestibular syndrome and vertigo
  64. · The great peripheral causes
  65. Cortical syndromes and aphasias
  66. · Brain lobes and their syndromes
  67. · Classification of aphasias
  68. Dementia syndrome
  69. · Etiological classification of dementia
  70. · Reversible dementias: the obligation of the internist
  71. Headache syndrome
  72. · Primary headaches
  73. · Secondary alarm headaches
  74. Complementary tests in neurological syndromes
  75. · Neuroimaging: CT vs. RM
  76. · Lumbar puncture and CSF analysis
  77. · Neurophysiology
  78. Diagnostic integration and synthesis
  79. · Syndromic decision map
  80. · The five closing principles

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Neurology
Category
Clinical Specialties
Type
Study Guide
Sections
80
Reviewed
2026-08-02
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