Major Neurological Syndromes
Major Neurological Syndromes — Expert Level Reference
How it begins
Los patrones sindrómicos cardinales con que la enfermedad neurológica se presenta ante el internista: conciencia, HTIC, meningitis, ictus, crisis, delirium, encefalopatías, síndromes motores, sensitivos, medulares, neuromusculares, de pares craneales, vestibulares, corticales, demencia y cefalea — con pruebas complementarias e integración diagnóstica.
What it covers
- The concept of major neurological syndrome
- · The temporal profile as the axis of reasoning
- Altered consciousness and coma syndrome
- · Clinical gradation of level of consciousness
- · Glasgow Coma Scale (GCS)
- · Examination of the comatose patient: signs of location of the trunk
- · Structural comma vs. toxic-metabolic
- · Systematic approach to coma of unknown cause
- · FOUR scale and limitations of the GCS
- · Prognosis of coma and brain death
- Intracranial hypertension syndrome
- · Clinical manifestations
- · Brain herniation syndromes
- · Management of HTIC and correlation with etiologies
- Meningeal syndrome
- · Exploration: signs of meningeal irritation
- · CSF analysis: the diagnostic key
- · Etiological correlation and management
- · Encephalitis: when the parenchyma becomes inflamed
- · Subarachnoid hemorrhage as meningeal syndrome
- Cerebrovascular syndrome (stroke)
- · Pathophysiology: ischemic penumbra
- · Etiological classification of ischemic stroke (TOAST)
- · Vascular topographic syndromes
- · Hemorrhagic stroke
- · Acute management and therapeutic correlation
- · Classic brainstem syndromes (alternating syndromes)
- · NIHSS scale and quantification of the deficit
- · Oxford Clinical Classification (Bamford / OCSP)
- Convulsive syndrome and status epilepticus
- · Classification of crises (ILAE)
- · Differential diagnosis: the great trap of syncope
- · Acute symptomatic crises: the internist approach
- · The postcritical period and Todd's paralysis
- · Study of the first crisis and considerations of chronic management
- Acute confusional syndrome (delirium)
- · Clinical subtypes
- · Delirium vs. dementia: the critical distinction
- · Etiology: the predisposing-precipitating model
- · Management
- Encephalopathic and dysautonomic syndromes
- · Major metabolic and toxic encephalopathies
- · Dysautonomic syndromes
- Pyramidal syndrome: upper motor neuron vs. lower
- · Amyotrophic lateral sclerosis: the paradigmatic mixed syndrome
- · Addressing weakness: locating the level
- Extrapyramidal and cerebellar syndromes
- · Extrapyramidal syndromes
- · Cerebellar syndrome
- Spinal cord syndrome
- · Topographic spinal syndromes
- Neuromuscular syndrome (PNS, junction and muscle)
- · Polyneuropathy and Guillain-Barré syndrome
- · Neuromuscular junction disorders
- · Myopathies
- Sensitive syndromes
- · Topographic patterns of sensory deficit
- · Semiology of neuropathic pain
- Cranial nerve and brainstem syndromes
- · Oculomotor and gaze syndromes
- · Facial paralysis: central vs. peripheral
- · Low torques and skull base syndromes
- Vestibular syndrome and vertigo
- · The great peripheral causes
- Cortical syndromes and aphasias
- · Brain lobes and their syndromes
- · Classification of aphasias
- Dementia syndrome
- · Etiological classification of dementia
- · Reversible dementias: the obligation of the internist
- Headache syndrome
- · Primary headaches
- · Secondary alarm headaches
- Complementary tests in neurological syndromes
- · Neuroimaging: CT vs. RM
- · Lumbar puncture and CSF analysis
- · Neurophysiology
- Diagnostic integration and synthesis
- · Syndromic decision map
- · The five closing principles
The complete study guide is in the app
This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.
- Subject
- Neurology
- Category
- Clinical Specialties
- Type
- Study Guide
- Sections
- 80
- Reviewed
- 2026-08-02